摘要：
In the recent years, Mn4+-doped phosphors for indoor plant cultivation have received extensive concern owing to the far-red emission that can match well with the absorption spectra of plant pigments. Whereas, many Mn4+-doped phosphors still face some challenges such as poor light efficiency and low thermal stability. It is an effective way to resolve these problems via cation vacancies engineering. Herein, the Ca14-xAl10Zn6-yO35: Mn4+ phosphors are successfully synthesized by combustion method. The luminescence intensity of Ca14-xAl10Zn6-yO35: Mn4+ phosphor is enhanced through engineering Ca2+ and Zn2+ vacancies according to the charge compensation mechanism. The optimal content of each Ca2+ and Zn2+ vacancy is equal to be 0.3. Furthermore, the defect formation is accompanied with lattice distortion, which plays a vital role in driving the excited phonon traps to reduce the energy loss by non-radiation transitions. Therefore, the thermal stability of Ca14-xAl10Zn6-yO35: Mn4+ phosphor is also improved via engineering cation vacancies. In addition, the Ca14-xAl10Zn6-yO35: Mn4+ phosphors can be effectively excited by blue light and it exhibits far-red emission due to the Mn4+ spin-forbidden E-2 -> (4)A(2) transition. The results suggest that the Ca14-xAl10Zn6-yO35: Mn4+ phosphors can have a tremendous potential in indoor plant cultivation.
摘要：
In this study, the ABE was firstly mixed with the pure gasoline, and stored in different containers to make the different sample fuels (referred as ABE10, ABE20, and ABE30). Then, the effects of the ABE ratio, spark timing and lambda were comprehensively investigated on the performance and emissions characteristics of the high-speed SI engine. The results indicated that the high-speed SI engine fuelled with ABE30 boasted the largest power, and followed by ABE20 and ABE10, while the pure gasoline generated the lowest output power. The lean burn limitation of the high-speed SI engine was greatly extended with increased the ABE ratio in the gasoline. Specifically, an extra 11.7% output power was obtained when the high-speed SI engine fuelled with ABE30 compared the pure gasoline. In addition, the higher ABE ratio in the ABE/gasoline blends yielded higher laminar flame speed of the ABE/gasoline, which increased the combustion rate and reduced the flame quenching distance near the cold wall, and thereby extending the lean-burn limitation. Apart from that, the NO emission formation was sensitive to the spark timing, and reached a peak value at the stoichiometric air/fuel ratio. The formation of CO and HC emissions did not show a strong relationship with the spark timing, and achieved a minimum value at the stoichiometric air/fuel ratio. Last, the NO emission formation dramatically decreased with increasing the ABE ratio in the ABE/gasoline blends, since the charge cooling effect reduced the in-cylinder peak combustion temperature.
摘要：
BACKGROUND: Recent work suggests that the social component of anhedonia is more associated with suicide ideation than the other component of pleasure. The present study investigated the differential effects of state and trait social anhedonia on suicidal ideation across two undergraduate samples based on the Interpersonal Theory and Three-Step Theory of Suicide. METHODS: State social anhedonia was assessed with a single item (Loss of Interest in People) extracted from the Beck Depression Inventory, while trait social anhedonia was assessed using the Anticipatory and Consummatory Interpersonal Pleasure Scale. Suicidal ideation was re-administered at a 3-month follow-up. RESULTS: In Study 1, higher state social anhedonia was associated with greater levels of suicidal ideation, while trait social anhedonia moderated the relationship between thwarted belongingness, perceived burdensomeness and suicidal ideation. In Study 2, state social anhedonia was margin significant predictor of suicidal ideation, while trait social anhedonia moderated the relationship between psychological pain and suicidal ideation. CONCLUSIONS: These findings confirmed the presence of two different effects on suicidal ideation in state and trait social anhedonia: state social anhedonia directly was associated with suicidal ideation, while trait social anhedonia was indirectly related through their effects on other risk factors of suicidality.
摘要：
An effective adsorbent towards fluoroquinolone antibiotics was synthesized via a facile two-step approach, the co-precipitation of Fe, Mn with vinasse wastes and then pyrolysis under controlled conditions which denoted as FMB. Its adsorption behavior was examined based on a batch adsorption experiment of fluoroquinolone antibiotics pefloxacin (PEF) and ciprofloxacin (CIP). Experimental factors, such as pH, adsorbent dose, ionic strength, contact time and temperature have done a great deal to influence the adsorption of PEF and CIP. The FMB demonstrated excellent performance in reusability tests towards to both PEF and CIP, which showed that the recycling efficiency of PEF and CIP could remain similar to 55% and similar to 80% after five recycle cycles, respectively. The dominated adsorption mechanisms included pore filling effect, pi-pi stacking interaction, pi-pi EDA, hydrogen bonding and hydrophobicity. Overall, this work presented FMB was recognized as an effective, environmental-friendly and magnetically separable adsorbent for alleviating fluoroquinolone antibiotics contamination from water. (C) 2019 Elsevier B.V. All rights reserved.
关键词：
Brassica oleracea L. var. italica;Selenium;Biofortified;Bioactive substance;Sulforaphane;Glucosinolate;Myrosinase
摘要：
The effects of S (as sulphate) and Se (as selenite) treatment (S mM/Se mu M: 1/0, 1/50, 1/100, 1/150, 4/0, 4/50, 4/100, and 4/150) on the production of sulforaphane (an anticancer compound), the accumulation of its precursor substance, and the expression of genes related to glucoraphanin biosynthesis in broccoli were examined. Sulforaphane yield and myrosinase activity increased significantly with the combined application of 4 mM S and 100 mu M Se on broccoli. Furthermore, the concentrations of glucoraphanin (a sulforaphane precursor) and methionine (a glucoraphanin substrate) slightly changed after Se application. And the strong anticancer activity of compound Se-SMC was further improved. Analysis of related gene expression showed that MY, which encodes myrosinase, was strongly induced by Se treatment. Thus, the myrosinase activity induced by Se treatment is the dominant factor affecting sulforaphane yield from glucoraphanin hydrolyzation. Selenium-sulfur biofortification provides a technical support for the cultivation of broccoli with high sulforaphane and high anti-cancer selenium compounds.
摘要：
Non-structural protein 1 (NS1) of influenza virus is a multifunctional protein that plays an important role in virus replication and virulence. In this study, an acetylation modification was identified at the K108 residue of the NS1 protein of H1N1 influenza virus. To further explore the function of the K108 acetylation modification of the NS1 protein, a deacetylation-mimic mutation (K108R) and a constant acetylation-mimic mutation (K108Q) were introduced into the NS1 protein in the background of A/WSN/1933 H1N1 (WSN), resulting in two mutant viruses (WSN-NS1-108R and WSN-NS1-108Q). In vitro and mouse studies showed that the deacetylation-mimic mutation K108R in the NS1 protein attenuated the replication and virulence of WSN-NS1-108R, while the constant acetylation-mimic mutant virus WSN-NS1-108Q showed similar replication and pathogenicity as the wild-type WSN virus (WSN-wt). The results indicated that acetylation at K108 of the NS1 protein has an important role in the replication and virulence of influenza virus. To further explore the potential mechanism, the type I interferon (IFN-I) antagonistic activity of the three NS1 proteins (NS1-108Q, NS1-108R, and NS1-wt) was compared in cells, which showed that the K108R mutation significantly attenuated the IFN-β antagonistic activity of the NS1 protein compared with NS1-wt and NS1-108Q. Both NS1-wt and NS1-108Q inhibited the IFN-β response activated by RIG-I CARD domain, MAVS, TBK1, and IRF3 more efficiently than the NS1-108R protein in cells. Taken together, the results indicated that acetylation at NS1 K108 is important for the IFN antagonistic activity of the NS1 protein and virulence of the influenza virus.
通讯机构：
[Huang, Min] H;Hunan Agr Univ, Coll Agron, Crop & Environm Res Ctr, Changsha 410128, Peoples R China.
摘要：
Soil microorganisms play an important role in determining productivity of agro-ecosystems. This study was conducted to compare diversity, richness, and structure (relative abundance at the phylum level) of soil bacterial communities among three rice-based cropping systems, namely, a winter fallow-rice-rice (FRR), green manure (Chinese milk vetch)-rice-rice (MRR), and oilseed rape-rice-rice (ORR), in which MRR and ORR had significantly higher productivity than FRR. A 16S rRNA gene sequence analysis showed that no significant differences were observed in diversity and richness indices (observed species, Shannon, Simpson, Chao1, abundance-based coverage estimators, and phylogeny-based metrics) of soil bacterial communities among the three cropping systems. However, relative abundances of dominant phyla in soil bacterial communities, including Proteobacteria, Acidobacteria, Nitrospirae, Gemmatimonadetes, and Verrucomicrobia, were significantly different among the three cropping systems. In particular, a significant reduction in the relative abundance of Nitrospirae was observed in both MRR and ORR compared with FRR. These results indicate that bacterial community structure was affected by cropping systems in the tested paddy soils. Based on the results of our studies and existing knowledge bases, we speculate that benefits to rice yield may be obtained by reducing the relative abundance of Nitrospirae and increasing the ratio of abundances of Proteobacteria/Acidobacteria in paddy soils.
关键词：
Chinese fir;Plantation;Soil nutrient;Phospholipid fatty acids;Illumina sequencing
摘要：
Bacteria play determining roles in forest soil environment and contribute to essential functions in the cycling of nitrogen (N) and phosphorus (P). Understanding the effects of different fertilizer applications, especially successive fertilization, on soil properties and bacterial community could reveal the impacts of fertilization on forest soil ecology and shed light on the nutrient cycling in forest system. This study aimed to evaluate the impacts of successive mineral N (NH4NO3) and P (NaH2PO4) fertilization at different rates, alone or together, on soil bacterial biomass and communities at 0–5, 5–10, and 10–20 cm. Compared with the control, N fertilization decreased soil pH, but P alone or with N fertilization had negligibly negative impacts on soil pH. Different mineral fertilizer applications, alone or together, showed no significant effects on soil organic matter contents, relative to the control treatment. Bacterial biomass remained stable to different fertilizations but decreased with sampling depths. Sole N or P fertilization, rather than combined fertilizations, significantly changed soil bacterial community structures. Our results demonstrated that mineral N or P fertilization alone significantly affected bacterial community structures rather than biomass in the plantation soils.
• Impacts of successive mineral fertilization on soil bacteria were determined.
• Mineral fertilization showed negligible impacts on bacterial biomass.
• N additions stimulated Chloroflexi relative abundances.
• Mineral N or P fertilization significantly altered bacterial community structure.
摘要：
The effects of S and Se treatment on cabbage, especially the interactions of S and Se metabolism with the biosynthesis of glucosinolate (GSL), including glucoraphanin, which is a major aliphatic GSL in cruciferous vegetables and the precursor of the anticancer compound sulforaphane, were examined. Cabbage plants were treated with sulfate and selenite (SeO32-), and the total S, Se, and GSL contents of cabbage head and outer foliage leaves were measured. Results showed that selenite treatment was beneficial to GSL biosynthesis and Se accumulation in cabbage head and outer foliage leaves. GSL synthesis was induced by exogenous selenite-elevated sulfate treatment at certain concentration ratios, i.e., 50-mu M selenite + 1-mM sulfate or 100-mu M selenite + 4-mM sulfate. A high exogenous sulfate concentration was more favorable to GSL accumulation than a low sulfate concentration. According to the relative expression of genes on GSL synthesis, an increase in the GSL content was attributed to the upregulation of gene expression and possible transportation from the outer foliage leaf to the head of cabbage. These results might be helpful for increasing the health benefits of cabbage by supplying exogenous S and Se. Further research should explore the effects of sulfate and selenite on GSL precursor substances to reveal the reason why total GSL contents increased.
摘要：
Adolescents with childhood trauma may be associated with psychotic-like experiences (PLEs) and is at high risk for later development of psychoses. Exploring early age risk factors for childhood trauma may provide useful information for prevention of mental disorders and improvement of mental health, yet no studies have examined the association between exposure to specific forms of trauma and different types of PLEs in a sample of Chinese adolescents. Thus, the Childhood Trauma Questionnaire-Short Form was used to measure five types of childhood trauma (emotional abuse, EA; physical abuse, PA; sexual abuse, SA; emotional neglect, EA; physical neglect, PA) in junior middle school students. And the positive subscale of Community Assessment of Psychic Experiences divided into four types (bizarre experiences, perceptual abnormalities, persecutory ideation and magical thinking) was used to measure PLEs. Then the possible associations among demographic information and specific types of childhood trauma on specific forms of PLEs was compared. The rates of EA, PA, SA, EA and PA were 14.2%, 13.0%, 16.1%, 60.0%, and 78.6%, respectively. Moreover, childhood trauma seems to be a main role in the development of PLE, and EA and SA patients are particularly likely to experience PLEs.
摘要：
Subcritical water can effectively hydrolyze pectin into smaller molecules while still maintaining its functional regions. Pectic heteropolysaccharide can mediate immune regulation; however, the possible effects of subcritical water-hydrolyzed citrus pectin (SCP) on the immune response remain unclear. Therefore, the effects of SCP on immunomodulatory functions and intestinal microbial dysbiosis were investigated using a cyclophosphamide-induced immunosuppressed mouse model. In this research, immunosuppressed ICR mice were administrated with SCP at dosages of 300/600/1200 mg/kg.bw by oral gavage, and body weight, immune organ indexes, cytokines, and gut microbiota were determined. The results showed that subcritical water treatment decreased the molecular mass and increased the content of galacturonic acid in citrus pectin hydrolysates. Meanwhile, the treatment with SCP improved immunoregulatory functional properties and bioactivities over the original citrus pectin. For example, SCP protected immune organs (accelerated recovery of immune organ indexes) and significantly enhanced the expression of immune-related cytokines (IL-2, IL-6, IFN-gamma, and TNF-alpha). The results of the 16S rDNA sequencing analysis on an IlluminaMiSeq platform showed that SCP normalized Cy-induced gut dysbiosis. SCP ameliorated Cy-dependent changes in the relative abundance of several taxa, shifting the balance back to normal status (e.g., SCP increased beneficial Muribaculaceae, Ruminococcaceae, Bacteroidaceae, and Prevotellaceae while decreasing pathogenic Brevundimonas and Streptococcus). The results of this study suggest an innovative application of citrus pectin as an immunomodulator.
通讯机构：
[Yang, Xuexian O.] U;Univ New Mexico, Dept Mol Genet & Microbiol, Sch Med, Albuquerque, NM 87131 USA.
摘要：
Maintenance of regulatory T (Treg) cells is crucial for the regulatory function of Treg cells in immune homeostasis and self-tolerance; however, the detailed underlying mechanisms remain elusive. In the current study, we found that the cytokine suppressor CIS (cytokine induced SH-2 protein) is required for maintenance of Treg cell identity. Mice with Treg-specific Cis-deficiency displayed aggravated experimental allergic asthma, and in adulthood, developed splenomegaly, lymphadenopathy and spontaneous eosinophilic airway inflammation, accompanied by accumulation of effector memory helper T (TH) cells. Cis-deficiency led to the loss of Foxp3 expression and the decrease in suppressive function of Treg cells. Cis-deficient Treg cells expressed TH2 cell signature genes, Gata3, Irf4 and Il4, and excessive interleukin-4-signal transducer and activator of transcription 6 (IL-4-STAT6) signals resulted in repressive chromatin modification in the Foxp3 locus and permissive modification in the Il4 loci. In vitro, blockade of IL-4 restored the expression of Foxp3 and the suppressive function of inducible Treg (iTreg) cells. Thus, we identified a novel feedback loop in stabilization of Treg cells and suppression of TH2-type inflammation in a Treg-intrinsic manner.
