Effects of Chitosan on Intestinal Inflammation in Weaned Pigs Challenged by Enterotoxigenic Escherichia coli

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xiao, Dingfu;Wang, Yongfei;Liu, Gang;He, Jianhua;Qiu, Wei;...

通讯作者：

Tang, Zhiru

作者机构：

[Ran, Maoliang; Xiao, Dingfu; He, Jianhua] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Hunan, Peoples R China.

[Wang, Yongfei; Feng, Zemeng] Twins Grp Co Ltd, Ctr Res & Dev, Nanchang, Jiangxi, Peoples R China.

[Liu, Gang; Yin, Yulong] Chinese Acad Sci, Inst Subtrop Agr, Hunan Engn & Res Ctr Anim & Poultry Sci, Changsha, Hunan, Peoples R China.

[Liu, Gang; Yin, Yulong] Chinese Acad Sci, Inst Subtrop Agr, Key Lab Agro ecol Processes Subtrop Reg, Changsha, Hunan, Peoples R China.

[Qiu, Wei] Hunan New Wellful Co LTD, Changsha, Hunan, Peoples R China.

通讯机构：

[Tang, Zhiru] S

Southwest Univ, Coll Anim Sci & Technol, Chongqing, Peoples R China.

语种：

英文

关键词：

Swine;Diarrhea;Diet;Cytokines;Inflammation;Inflammatory bowel disease;Protein expression;Gastrointestinal tract

期刊：

PLOS ONE

ISSN：

1932-6203

年：

2014

卷：

期：

页码：

e104192-

DOI：

10.1371/journal.pone.0104192

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31330075, 31301985]; Scientific Research Fund of Hunan Provincial Education Department Project of China [12B058]; National Program on Key Basic Research Project of ChinaNational Basic Research Program of China [2013CB127303]; Natural Science Foundation Project of CQ CSTCNatural Science Foundation Project of CQ CSTC [cstc2012jjA80001]; Chinese Academy of SciencesChinese Academy of Sciences [ISACX-LYQY-QN-1205, 2013T2S0014, 2013T2S0015, 2013T2S0012, 2013T1S0010, 2011T2S15]

机构署名：

本校为第一机构

院系归属：

动物科学技术学院

摘要：

The aim of this study was to investigate whether supplementation with chitosan (COS) could reduce diarrhea and to explore how COS alleviates intestinal inflammation in weaned pigs. Thirty pigs (Duroc×Landrace×Yorkshire, initial BW of 5.65±0.27) weaned at age 21 d were challenged with enterotoxigenic Escherichia coli during a preliminary trial period, and then divided into three treatment groups. Pigs in individual pens were fed a corn-soybean meal diet, that contained either 0 (control), 50 mg/kg chlortetracycline, or 300 mg/kg COS for 21 da...

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Effects of Chitosan on Intestinal Inflammation in Weaned Pigs Challenged by Enterotoxigenic Escherichia coli

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