Dietary l-glutamine supplementation improves pregnancy outcome in mice infected with type-2 porcine circovirus

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成果类型：

期刊论文

作者：

Ren, Wenkai;Luo, Wei;Wu, Miaomiao;Liu, Gang;Yu, Xinglong;...

通讯作者：

Yin, Yulong

作者机构：

[Liu, Gang; Ren, Wenkai; Wu, Miaomiao; Wu, Guoyao; Li, Teijun; Yin, Yulong] Chinese Acad Sci, Res Ctr Hlth Breeding Livestock & Poultry, Key Lab Agroecol Proc Subtrop Reg, Hunan Engn & Res Ctr Anim & Poultry Sci,Inst Subt, Changsha 410125, Hunan, Peoples R China.

[Ren, Wenkai; Fang, Jun] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Hunan, Peoples R China.

[Yu, Xinglong; Luo, Wei] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan, Peoples R China.

[Wu, Guoyao] China Agr Univ, State Key Lab Anim Nutr, Beijing 100193, Peoples R China.

[Wu, Guoyao] Texas A&M Univ, Dept Anim Sci, College Stn, TX 77843 USA.

通讯机构：

[Yin, Yulong] C

Chinese Acad Sci, Res Ctr Hlth Breeding Livestock & Poultry, Key Lab Agroecol Proc Subtrop Reg, Hunan Engn & Res Ctr Anim & Poultry Sci,Inst Subt, Changsha 410125, Hunan, Peoples R China.

语种：

英文

关键词：

Porcine circovirus type 2;Pigs;Nutrition;Amino acids;Reproductive failure

期刊：

Amino Acids

ISSN：

0939-4451

年：

2013

卷：

期：

页码：

479-488

DOI：

10.1007/s00726-011-1134-5

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31110103909, 30901041, 30972167, 30901040, 30928018, 30972156, 30871801, 30828024, 30828025, 30771558, 30700581]; National Basic Research ProjectNational Basic Research Program of China [2009CB118800]; CAS/SAFEA International Partnership Program for Creative Research TeamsChinese Academy of Sciences; Thousand-People-Talent program at China Agricultural University; Ministry of Science and Technology of People's Republic of ChinaMinistry of Science and Technology, China [2010GB2D200322]; Hunan Provincial Natural Science Foundation of ChinaNatural Science Foundation of Hunan Province [10JJ2028]; Texas AgriLife Research [8200]

机构署名：

本校为其他机构

院系归属：

动物医学院

生物科学技术学院

摘要：

Porcine circovirus type 2 (PCV2) causes reproductive failure in swine. As glutamine can enhance immune function in animals, this study was conducted with mice to test the hypothesis that dietary glutamine supplementation will improve pregnancy outcome in PCV2-infected dams. Beginning on day 0 of gestation, mice were fed a standard diet supplemented with 1.0% l-glutamine or 1.22% l-alanine (isonitrogenous control). All mice were infected with PCV2 (2000 TCID 50) on day 10 of gestation. On day 17 of gestation, six mice from each group were euthan...

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Dietary l-glutamine supplementation improves pregnancy outcome in mice infected with type-2 porcine circovirus

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