The achievement of the human genome planning (HGP) brings bioscience into the post-genomic era. Functional analysis of new genes becomes the highlight of the bioscientific researches. Strategies of functional genes analysis become more advanced and more diversified. This review is mainly related to the basic principle, specificity, advantages and disadvantages of several main strategies of gene functional analysis including gene knock-out, antisense technic, “dominat negative' strategy , gene inducible ov...
