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Click synthesis of glycosylated porphyrin-cored PAMAM dendrimers with specific recognition and thermosensitivity

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成果类型:
期刊论文
作者:
Chang, Dan-Dan;Yang, Wei-He;Dai, Xiao-Hui*;Wang, Ji-Xiang;Chen, Li*;...
通讯作者:
Dai, Xiao-Hui;Chen, Li
作者机构:
[Wang, Ji-Xiang; Dai, Xiao-Hui; Chen, Li; Yang, Wei-He; Yan, Yong-Sheng; Chang, Dan-Dan; Pan, Jian-Ming] Jiangsu Univ, Sch Chem & Chem Technol, Dept Chem Engn, Zhenjiang 212013, Peoples R China.
[Dai, Xiao-Hui; Chen, Li; Yan, Yong-Sheng] Jiangsu Univ, Inst Green Chem & Chem Technol, Zhenjiang 212013, Peoples R China.
[Dai, Yi-Rong] Human Agr Univ, Hosp Affiliated, Zhenjiang 212013, Peoples R China.
通讯机构:
[Dai, XH; Chen, L] J
Jiangsu Univ, Sch Chem & Chem Technol, Dept Chem Engn, Zhenjiang 212013, Peoples R China.
Jiangsu Univ, Inst Green Chem & Chem Technol, Zhenjiang 212013, Peoples R China.
语种:
英文
关键词:
Glycosylated porphyrin;Dendrimers;Thermosensitivity;Specific recognition;PDT
期刊:
Journal of Polymer Research
ISSN:
1022-9760
年:
2018
卷:
25
期:
12
页码:
1-12
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21004031]; Natural Science Foundation of Jiangsu ProvinceNatural Science Foundation of Jiangsu Province [BK2011459]; Practice Innovation Program of Jiang Su [SJZZ-0138]; Jiangsu University Science and Technology Project for Youth Support Fund
机构署名:
本校为其他机构
摘要:
Glycoporphyrin dendrimers have received increasing attentions due to their distinct physical and chemistry properties, such as fluorescence and water solubility. They also acted as a promising photodynamic therapy (PDT) sensitizer and used in the study of carbohydrate-protein interaction. In this study, different generations of porphyrin-cored dendrimers consisting of glycosylated siloxane-poly (amido amine) typed dendron (PP-Si-PAMAM-Dm-Lac, m = 1, 2, and 3), multifunctional specific-targeting sensitizers, had been synthesized via click reacti...

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