会议名称:
Joint 16th International Symposium on Trace Elements in Man and Animals (TEMA) / 12th Conference of the International-Society-for-Trace-Element-Research-in-Humans (ISTERH) / 13th Conference of the Nordic-Trace-Element-Society (NTES)
会议名称:
Joint 16th International Symposium on Trace Elements in Man and Animals (TEMA) / 12th Conference of the International-Society-for-Trace-Element-Research-in-Humans (ISTERH) / 13th Conference of the Nordic-Trace-Element-Society (NTES)
摘要:
Accurate and real-time water quality assessment is an important way to ensure healthy aquaculture and protect the water environment. Due to the diversity, nonlinear and uneven distribution of aquaculture water quality parameters, it's very difficulty to assess the water quality. In this paper, the accurate water quality parameters are obtained by an adaptive weighted fusion method, then the water quality is assessment by the BP neural network, thus the software of the monitoring and evaluation system for ecological water quality is developed. The test results show that the accuracy of the water quality assessment system is 93.3%, which has good practicability.
摘要:
Phosphorylation of target proteins by protein kinases leads to the activation of cellular signaling pathways, which induce a great number of biological processes including cell growth, differentiation, development, and death. Although the activities of protein kinases are stringently regulated in homeostasis system, protein kinases can be deregulated under pathological conditions, leading to perturbation of protein kinase-mediated cell signaling pathways and resulting in various disorders including cancer, diabetes, and inflammation. The data from the Human Genome Project has revealed that 518 protein kinases are encoded in the human genome, thereby creating an enormous repertoire of potential targets for chemoprevention. Polyphenols, as integral constituents of the diet, have been proposed to exert beneficial effects in a multitude of disease states. Recent studies have suggested that the cellular effects of polyphenols are, at least partly, mediated by their interactions with protein kinases central to intracellular signaling cascades. In the present study, we investigated the interaction of polyphenols-protein kinases by pull down assay, affinity assay and computer simulation. The results revealed that some polyphenols compounds suppressed the phosphorylation of various protein kinases with different affinity and selectivity. Finally, we discussed the impact of these polyphenols-protein kinases interactions on cellular signaling and chemoprevention.
作者机构:
[Zhu, X. Z.; Tian, L. X.; Liu, Y. -J.] Sun Yat Sen Univ, Inst Aquat Econ Anim, Sch Life Sci, W Guangzhou, Peoples R China.;[Mai, K. S.] Ocean Univ China, Coll Fisheries, Qingdao, Peoples R China.;[Zhang, Q. H.; Zheng, C. Q.; Cai, M. C.; Zheng, S. X.] Guangdong Yuehai Feed Grp Co Ltd, Zhanjiang, Peoples R China.;[Pan, Q. J.] So Med Univ, Sch Basic Med Sci, Guangzhou, Guangdong, Peoples R China.;[Hu, Y.] Hu Nan Agr Univ, Coll Anim Sci & Technol, Changsha, Hunan, Peoples R China.
通讯机构:
[Liu, Y. -J.] S;Sun Yat Sen Univ, Inst Aquat Econ Anim, Sch Life Sci, 135 Xingang W, Guangzhou 510275, Guangdong, Peoples R China.
会议名称:
10th International Symposium on Digestive Physiology in Pigs
会议时间:
MAY 25-27, 2006
会议地点:
Vejle, DENMARK
会议主办单位:
Chinese Acad Sci, Inst Subtrop Agr, Changsha 410128, Hunan, Peoples R China.^Cent S Univ, Xiang Ya Med Sch, Mol Biol Res Inst, Changsha 410078, Hunan, Peoples R China.^Hunan Agr Univ, Dept Anim Sci, Changsha 410128, Peoples R China.^Texas A&M Univ, Dept Anim Sci, College Stn, TX 77843 USA.
摘要:
This study was conducted to test the hypothesis that porcine jejunal mucosal cells can degrade all essential amino acids (EAA). Jejunal mucosal cells (primarily enterocytes) were isolated from 50-day-old healthy pigs and incubated at 37 degrees C for 45 min in Krebs buffer containing plasma concentrations of amino acids and one of the following L-[1-C-14]- or L-[U-C-14]-amino acids plus unlabeled tracers at 0.5, 2, or 5 mM: histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine. There was active transamination of leucine, isoleucine and valine in the cells (1.35-2.5 nmol/mg protein per 45 min at 2 mM), with most (67-71%) of their alpha-ketoacids released into the medium. In contrast, catabolism of methionine and phenylalanine was negligible (0.04-0.05 nmol/mg protein per 45 min at 2 mM) and that of other EAA was completely absent in these cells. These results indicate that intestinal mucosal cells are a site for the substantial degradation of branched-chain amino acids but not other EAA in pigs. (c) 2007 Elsevier B.V. All rights reserved.
摘要:
Two digestibility experiments were carried out to comparatively measure true phosphorus (P) digestibility and the faecal endogenous P loss associated with soybean meat (SBM) and wheat middling meal (WM) for growing pigs by the simple linear regression analysis technique and the substitution method. Eight barrows, with an average initial body weight 21 kg, were randomly divided into two groups of four pigs with each group being fed four test diets according to a 4 x 4 Latin square design. Eight maize starch-based diets containing four levels (on dry matter basis) of P (0.20, 0.24, 0.3 6 and 0.42%) and P (0. 181, 0.26, 0.36, and 0.43 %) were formulated from SBM and WM as a sole source of P, respectively. Chromic oxide (0.30%) was used as a digestibility marker. Each experimental period comprised 8 d with a 4-d adaptation and a 4-d collection of faecal samples. Levels of the assay ingredient substitutions had no effects (P > 0.05) on true P digestibility and the endogenous P loss associated with SBM and WM measured by the substitution method. There were no differences (P > 0.05) between the regression technique and the substitution method in measuring the true P digestibility (SBM: 49.4 +/- 3.51 vs. 50.6 +/- 2.4; WM: 63.7 +/- 5.0 vs. 63.2 +/- 5.4%) as well as the faecal endogenous P loss (SBM: 0.62 +/- 0.10 vs. 0.71 +/- 0.11 WM: 0.65 +/- 0.16 vs. 0.70 +/- 0.17 g/kg dry matter intake) for the growing pig. Thus, true P digestibility and the faecal endogenous P loss in feed ingredients for pigs may be measured by using the regression analysis technique and the substitution method. (c) 2007 Elsevier B.V. All rights reserved.