通讯作者：
Dr. Junpei Yue<&wdkj&>Prof. Xiongwei Wu<&wdkj&>Prof. Yuping Wu
作者机构：
Institute of Advanced Materials School of Energy Science and Engineering, Nanjing Tech University, Nanjing, 211816 Jiangsu Province, P.R. China;[Jun Mo; Jun Liu; Prof. Canming Liu; Dr. Xianxiang Zeng; Prof. Wenxin Zhou] College of Science, College of Agronomy, Hunan Agricultural University, Changsha, 410128 China;[Jie Huang] Chenzhou Branch Company of Sinopec Hunan Sale Co. LTD, Chenzhou, 423000 P.R. China;[Dr. Junpei Yue] CAS Key Laboratory of Molecular Nanostructure and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 China;[Dr. Xinhai Yuan; Prof. Yuping Wu] Institute of Advanced Materials School of Energy Science and Engineering, Nanjing Tech University, Nanjing, 211816 Jiangsu Province, P.R. China<&wdkj&>College of Science, College of Agronomy, Hunan Agricultural University, Changsha, 410128 China
通讯机构：
[Dr. Junpei Yue; Prof. Xiongwei Wu] C;[Prof. Yuping Wu] I;CAS Key Laboratory of Molecular Nanostructure and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 China<&wdkj&>Institute of Advanced Materials School of Energy Science and Engineering, Nanjing Tech University, Nanjing, 211816 Jiangsu Province, P.R. China<&wdkj&>College of Science, College of Agronomy, Hunan Agricultural University, Changsha, 410128 China<&wdkj&>College of Science, College of Agronomy, Hunan Agricultural University, Changsha, 410128 China<&wdkj&>CAS Key Laboratory of Molecular Nanostructure and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 China
关键词：
zinc-bromine battery;high voltage;high energy density;K+-conducting membrane;hybrid electrolytes
关键词：
Julia sets;buried component;singular perturbations
摘要：
Let f be a rational map with degree d\geq 2 whose Julia set is connected but not equal to the whole Riemann sphere. It is proved that there exists a rational map g such that g contains a buried Julia component on which the dynamics is quasiconformally conjugate to that of f on the Julia set if and only if f does not have parabolic basins and Siegel disks. If such g exists, then the degree can be chosen such that \deg (g)\leq 7d-2. In particular, if f is a polynomial, then g can be chosen such that \deg (g)\leq 4d+4. Moreover, some quartic and cubic rational maps whose Julia sets contain buried Jordan curves are also constructed.
关键词：
zinc-bromine battery;high voltage;high energy density;K+-conducting membrane;hybrid electrolytes
摘要：
The zinc-bromine redox flow battery (ZBB) is an ideal device of energy storage systems. Nevertheless, its energy density is relatively low compared to those of Li-ion batteries, due to its low output voltage. Herein, a high-voltage aqueous hybrid zinc-bromine battery system (AHZBBs) was developed, where K+-conducting membrane was used to segregate neutral-alkaline hybrid electrolytes and redox couples of Br-2/Br(-)and [Zn(OH)(4)](2-)/Zn at the positive and negative electrode. Benefited from an efficient and stable cathode catalyst (carbon-manganite nanoflakes), this AHZBB delivered a high average output voltage of 2.15 V and energy density of 276.7 Wh/kg without capacity attenuation after 200 cycles. More importantly, this work provides an efficient avenue to elevating the output voltage and energy density, and will strongly encourage studies on redox flow batteries.
摘要：
The microjetting processes of single-crystal fin with sinusoidal surface defects under laser loading and plane impact loading are investigated by using molecular dynamics simulations via the second nearest-neighbor modified embedded atom method potential. Simulation results exhibit that the jetting factors for laser loading and plane impact loading first increase with the increment of shock breakout pressure and then reach their own saturation values, in agreement with previous experimental observations. However, the jetting factor under laser loading saturates at relatively lower shock breakout pressure than its counterpart under plane impact loading. Structure analysis via x-ray diffraction and radial distribution function techniques indicates that the laser loading leads to higher melting degree, which further facilitates the ejection process. The spike velocity linearly depends on the shock breakout pressure for both loading methods, but the bubble velocity varies with the loading method. In addition, void nucleation and growth within the sample are observed for laser loading due to the interaction of release waves. The simulation results reveal the underlying mechanisms of ejection process under plane impact loading and laser loading, helping enhance the understanding of microjetting phenomena.
作者机构：
[Mai, Yaohua; Qiu, Shudi; He, Wenxin; Guo, Fei; Mai, YH; Guo, F; Hu, Jinlong] Jinan Univ, Coll Informat Sci & Technol, Inst New Energy Technol, Guangzhou 510632, Guangdong, Peoples R China.;[Peng, Chang; You, Jiang] Hunan Agr Univ, Coll Sci, Changsha 410128, Hunan, Peoples R China.;[Liu, Xianhu; Li, Chaohui] Zhengzhou Univ, Natl Engn Res Ctr Adv Polymer Proc Technol, Zhengzhou 450002, Henan, Peoples R China.
通讯机构：
[Mai, YH; Guo, F] J;[Peng, Chang] H;Jinan Univ, Coll Informat Sci & Technol, Inst New Energy Technol, Guangzhou 510632, Guangdong, Peoples R China.;Hunan Agr Univ, Coll Sci, Changsha 410128, Hunan, Peoples R China.
关键词：
energy-level alignments;hole-transport materials;inverted solar cells;polyfluorene copolymers
摘要：
Inverted perovskite solar cells (PSCs) that can be entirely processed at low temperatures have attracted growing attention due to their cost-effective production. Hole-transport materials (HTMs) play an essential role in achieving efficient inverted PSCs, as they determine the effectiveness of charge extraction and recombination at interfaces. Herein, three polyfluorene copolymers (TFB, PFB, and PFO) are investigated as HTMs for construction of inverted PSCs. It is found that the photovoltaic performance of the solar cells is closely correlated with the electronic properties of the HTMs. Due to its high mobility along with the favored energy-level alignment with perovskite, TFB shows superior charge extraction and suppressed interfacial recombination than PFB- and PFO-based devices, which delivers a high efficiency of 18.48% with an open-circuit voltage (V-OC) of up to 1.1 V. In contrast, the presence of a large energy barrier in the PFO-based devices results in substantial losses in both V-OC and photocurrent. These results demonstrate that TFB can serve as a superior HTM for inverted PSCs. Moreover, it is anticipated that the performance of the three HTMs identified here might guide the molecular design of novel HTMs for the manufacture of highly efficient inverted PSCs.
期刊：
European Journal of Medicinal Chemistry,2020年189:112028 ISSN：0223-5234
通讯作者：
Wang, LingLi;Zhou, Wen
作者机构：
[Zhou, Li] Hunan Agr Univ, Coll Sci, Furong Rd, Changsha 410128, Peoples R China.;[Chen, Wenming] Hunan Univ Chinese Med, Affiliated Hosp 1, Dept Pharmaceut, Prod Ctr, 95 Shaoshan Rd, Changsha 41007, Hunan, Peoples R China.;[Hu, Jiliang; Zhou, Wen; Cao, Chenyang; Ye, Wenchong; Wang, LingLi] Guangzhou Univ Chinese Med, Sch Pharmaceut Sci, E 232,Waihuan Rd, Guangzhou 510006, Peoples R China.;[Shi, Yonghui] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Pharm, Guangzhou 510120, Guangdong, Peoples R China.
通讯机构：
[Wang, LL; Zhou, W] G;Guangzhou Univ Chinese Med, Sch Pharmaceut Sci, E 232,Waihuan Rd, Guangzhou 510006, Peoples R China.
关键词：
CYP1B1;Click reaction;PROTACs;Reversal of drug resistance;alpha-Naphthoflavone-based conjugates
摘要：
Extrahepatic cytochrome P450 161 (CYP1B1), which is highly expressed in various tumors, is an attractive and potential target for cancer prevention, therapy, and reversal of drug resistance. CYP1B1 inhibition is the current predominant therapeutic paradigm to treating CYP1B1-mediated malignancy, but therapeutic effect has little success. Herein, we reported CYP1B1 degradation in place of CYP1BI inhibition for reversing drug resistance toward docetaxel in CYP1B1-overexpressing prostate cancer cell line DU145 using a PROTAC strategy. Replacing chlorine atom of a CYP1B1 selective inhibitor we found previously with ethynyl, we got the resulting alpha-naphthoflavone derivative 5 which kept strong inhibition against CYP1B1 (IC50 = 0.4 +/- 0.2 nM) and high selectivity. Coupling of 5 with thalidomide derivatives of varying chain lengths afforded conjugates 6A-D via click reaction. In vitro cell-based assay indicated that 6C was more effective in eliminating drug resistance of CYP1B1-overexpressed DU145 cells compared with other analogues. Western blotting analysis showed CYP1B1 degradation was one main reason for the reversal of drug resistance to docetaxel and the effect was obtained in a concentration-dependent manner. This work is the first attempt to overcome CYP1B1-mediated drug resistance via CYP1B1 degradation instead of CYP1B1 inhibition, which could provide a new direction toward eliminating drug resistance. (C) 2020 Elsevier Masson SAS. All rights reserved.
作者机构：
[Hu, Renzong; Zhu, Min; Wen, Gang; Liang, Tao; Tan, Liang; Liu, Jun] South China Univ Technol, Sch Mat Sci & Engn, Guangdong Prov Key Lab Adv Energy Storage Mat, Guangzhou 510640, Peoples R China.;[Liu, Hui] Hunan Agr Univ, Coll Sci, Changsha 410128, Hunan, Peoples R China.;[Zhang, Yao; Ouyang, Yunpeng] Sunwoda Elect Co Ltd, SUNWODA SCUT Joint Lab Adv Energy Storage Technol, Shenzhen 518107, Peoples R China.
通讯机构：
[Hu, Renzong] S;South China Univ Technol, Sch Mat Sci & Engn, Guangdong Prov Key Lab Adv Energy Storage Mat, Guangzhou 510640, Peoples R China.
关键词：
Full cell performance;Tin oxide;Anode materials;Coulombic efficiency
摘要：
Despite there being many reports on SnO2-based anode materials, most of the electrode materials are tested in half cells using lithium metal with unlimited lithium-ion sources as the counter electrode, which may conceal the real properties of these composites to a certain extent. In this study, a ternary SnO2-Co-C composite was fabricated by a scalable ball milling strategy. The composite exhibited high initial Coulombic efficiency (ICE, > 80%), a large capacity (similar to 900 mA h g(-1)) and superior cycling stability (capacity retention more than 99% after 100 cycles) in half cells. Furthermore, coin-type full cells in which the ternary SnO2 -Co-C anodes were paired with different cathodes were demonstrated. A LiFePO4 vertical bar vertical bar SnO2-Co-C full cell tested at 0.5-3.4 V exhibited an ICE of 75.1% and an initial discharge capacity of 906 mA h g(-1), which were close to those of the SnO2-Co-CIILi half cells. By analyzing the cycling performance and characteristics of the charge/discharge process for the full cells with different capacity ratios of cathode/anode, it was confirmed that the capacity decay of the full cells was due to the continuous consumption of Li+ ions during cycling. Hence, the testing voltage windows were adjusted according to the lithiation/de-lithiation behavior of the SnO2. On this basis, the LiFePO4 vertical bar vertical bar SnO2-Co-C full cells tested at 2.3-3.4 V and the LiCoO2 vertical bar vertical bar SnO2-Co-C full cells tested at 2.60-3.75 V exhibited excellent cycling stability, demonstrating 80.3% and almost 100% capacity retention after 100 cycles, respectively, thereby laying a foundation for the practical application of advanced SnO2-based anodes in lithium-ion batteries. (C) 2020 Elsevier Ltd. All rights reserved.
