The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model

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成果类型：

期刊论文

作者：

Xie, Ling;Zhong, Xiaohong;Liu, Dongbo;Liu, Lin;Xia, Zhilan*

通讯作者：

Xia, Zhilan

作者机构：

[Zhong, Xiaohong; Liu, Dongbo; Xia, Zhilan; Xie, Ling] Hunan Agr Univ, Coll Hort & Landscape Architecture, Changsha, Hunan, Peoples R China.

[Liu, Dongbo; Xie, Ling] State Key Lab Subhlth Intervent Technol, Changsha, Hunan, Peoples R China.

[Liu, Lin] Hunan Univ Chinese Med, Affiliated Hosp 1, Changsha, Hunan, Peoples R China.

[Xia, Zhilan; Xie, Ling] Hunan Engn Res Ctr Edible Fungi, Changsha, Hunan, Peoples R China.

通讯机构：

[Xia, Zhilan] H

Hunan Agr Univ, Coll Hort & Landscape Architecture, Changsha, Hunan, Peoples R China.

Hunan Engn Res Ctr Edible Fungi, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

Freeze-dried powder from Ganoderma lucidum mycelia;Rrecurrent oral ulcer;Rregulatory T cells;T-helper cells 17

期刊：

BMC Complementary Medicine and Therapies

ISSN：

2662-7671

年：

2017

卷：

期：

页码：

1-11

DOI：

10.1186/s12906-017-2021-8

基金类别：

This work was supported by the National Key Technology Research and Development Program of the Ministry of Science and Technology of China(number: 2013BAD16B00).

机构署名：

本校为第一且通讯机构

院系归属：

园艺园林学院

摘要：

Conventional scientific studies had supported the use of polysaccharides and β-glucans from a number of fungi, including Ganoderma lucidum for the treatment of recurrent oral ulceration (ROU). Our aim of the present study was to evaluate whether freeze-dried powder from G. lucidum mycelia (FDPGLM) prevents ROU in rats. A Sprague-Dawley (SD) rat model with ROU was established by autoantigen injection. The ROU rats were treated with three different dosages of FDPGLM and prednisone acetate (PA), and their effects were evaluated according to the c...

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The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model

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