期刊论文

In Vitro Bacteriostasis of Fruit Pulp Extract of Caulis Sinomenii on the Main Pathogens of Acne

中文

中国皮肤性病学杂志

1001-7089

2021

35

09

969-974

10.13735/j.cjdv.1001-7089.202103120

长沙市科技计划项目（k11907047）； 企业合作项目（2021kjc-js008）； 湖南省教育厅科学研究项目（20A259）； 湖南省自然科学基金项目（2020JJ4043）；

本校为第一机构

目的探究青风藤果浆萃取物对痤疮致病菌的抑菌活性,为青风藤果浆萃取物治疗痤疮提供实验依据。方法采集新鲜青风藤成熟期果实制备果浆,应用乙酸乙酯进行萃取,获得青风藤果浆萃取物。通过测定抑菌圈直径、最低抑菌浓度、时间动力学曲线及菌种的生长曲线判断青风藤果浆萃取物的抑菌活性。结果青风藤果浆萃取物有较好的抑菌活性,对表皮葡萄球菌的抑菌圈直径为（30.86±0.11） mm,最低抑菌浓度为25 mg/mL;对金黄色葡萄球菌的抑菌圈直径为（21.29±0.59） mm,最低抑菌浓度为35 mg/mL;对痤疮丙酸杆菌的抑菌圈直径为（30.16±0.88） mm,最低抑菌浓度为25 mg/mL,通过时间动力学曲线和菌种的生长曲线发现...

Objective To explore the antibacterial activity of fruit pulp extract of Caulis Sinomenii on acne pathogens, so as to provide the experimental basis on the treatment of acne by fruit pulp extract of Caulis Sinomenii. Methods Collected fresh mature fruit of Caulis Sinomenii to prepare fruit pulp,and Caulis Sinomenii pulp extract was extracted by ethyl acetate. The antibacterial activity of Caulis Sinomenii pulp extract was measured by the diameter of the inhibition zone,the minimum inhibitory concentration, the time kinetic curve and the growth ...