Dark tea extracts: Chemical constituents and modulatory effect on gastrointestinal function

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成果类型：

期刊论文

作者：

Gong, Zhi-ping;Ouyang, Jian;Wu, Xiang-lan;Zhou, Fang;Lu, Dan-Ming;...

通讯作者：

Liu, Zhong-hua;Zhu, Ming-zhi;Wang, Qi-ye

作者机构：

[Gong, Zhi-ping] Zhejiang Univ, Affiliated Hosp 1, Sch Med, Hangzhou 310003, Peoples R China.

[Lin, Hai-yan; Huang, Jian-an; Liu, Zhong-hua; Liu, ZH; Zhu, Ming-zhi; Liu, Chun-fang; Wu, Xiang-lan; Zhang, Jing-chi; Li, Neng-xin; Zhou, Fang; Song, Yu-xin; Miao, Feng; Zhao, Chen-jie; Li, Yi-long; Ouyang, Jian; Zhu, Wan; Cai, Shu-xian; Lu, Dan-Ming] Hunan Agr Univ, Coll Hort, Natl Res Ctr Engn Technol Utilizat Funct Ingredie, Key Lab Tea Sci,Minist Educ, Changsha 410128, Peoples R China.

[Lin, Hai-yan; Huang, Jian-an; Liu, Zhong-hua; Liu, Chun-fang; Wu, Xiang-lan; Zhang, Jing-chi; Li, Neng-xin; Zhou, Fang; Song, Yu-xin; Zhu, Ming-zhi; Miao, Feng; Zhao, Chen-jie; Li, Yi-long; Ouyang, Jian; Zhu, Wan; Cai, Shu-xian; Lu, Dan-Ming] Hunan Agr Univ, Hunan Prov Key Lab Germplasm Innovat & Utilizat C, Changsha 410128, Peoples R China.

[Wang, Qi-ye] Hunan Normal Univ, Coll Life Sci, Hunan Prov Key Lab Anim Intestinal Funct & Regula, Hunan Int Joint Lab Anim Intestinal Ecol & Hlth, Changsha 410081, Peoples R China.

[Zeng, Xin] Huaibei Normal Univ, Coll Life Sci, Huaibei 235000, Peoples R China.

通讯机构：

[Liu, ZH; Zhu, MZ; Wang, Qi-ye] H

Hunan Agr Univ, Coll Hort, Natl Res Ctr Engn Technol Utilizat Funct Ingredie, Key Lab Tea Sci,Minist Educ, Changsha 410128, Peoples R China.

Hunan Normal Univ, Coll Life Sci, Hunan Prov Key Lab Anim Intestinal Funct & Regula, Hunan Int Joint Lab Anim Intestinal Ecol & Hlth, Changsha 410081, Peoples R China.

语种：

英文

关键词：

Dark tea;Gastrointestinal function;Gastrointestinal transit;Antibiotic;Restoration;Intestinal microbes

期刊：

Biomedicine & Pharmacotherapy

ISSN：

0753-3322

年：

2020

卷：

130

页码：

110514

DOI：

10.1016/j.biopha.2020.110514

基金类别：

This work is supported by National Key R&D Program of China (Grant no. 2018YFC1604405 ), National Major R & D Project in China (Grant no. 2017YFD0400803 ), China Tea Research System Project (CARS-19-09B), Open Foundation of Hunan Provincial Key Laboratory for Germplasm Innovation and Utilization of Crop (Grant no. 18KFXM10 ), China Postdoctoral Science Foundation (Grant no. 2018M632962 ), and Hunan Provincial Natural Science Foundation of China (Grant no. 2019JJ50238 ). These funders played no roles in the study design, data collection and analysis, and decision to publish.

机构署名：

本校为通讯机构

院系归属：

园艺园林学院

摘要：

Processing of dark tea varieties, such as Fu brick tea, Liupao tea, Qianliang tea, and Qing brick tea, includes solid-state fermentation involving microorganisms. In this study, we analyzed the major chemical constituents of dark tea extracts and evaluated their modulatory effect on the gastrointestinal function in normal mice, including the improvement of gastrointestinal transit and intestinal microbial, as well as the attenuation of intestinal microbial dysbiosis and intestinal pathological damage, and the adjustment of immune function in antibiotic-treated mice. Substantial differences in ...

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Dark tea extracts: Chemical constituents and modulatory effect on gastrointestinal function

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