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The synergistic effects of polyphenols and intestinal microbiota on osteoporosis

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成果类型:
期刊论文
作者:
Wang, Keyu;Hu, Siwang
通讯作者:
Hu, SW
作者机构:
[Hu, Siwang; Hu, SW; Wang, Keyu] Wenzhou Med Univ, Peoples Hosp Wenling 1, Orthoped Ctr, Affiliated Wenling Hosp, Wenling, Zhejiang, Peoples R China.
[Wang, Keyu] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha, Hunan, Peoples R China.
通讯机构:
[Hu, SW ] W
Wenzhou Med Univ, Peoples Hosp Wenling 1, Orthoped Ctr, Affiliated Wenling Hosp, Wenling, Zhejiang, Peoples R China.
语种:
英文
关键词:
gut microbiota;immune system;osteoporosis;pathway;polyphenol
期刊:
FRONTIERS IN IMMUNOLOGY
ISSN:
1664-3224
年:
2023
卷:
14
页码:
1285621
基金类别:
The author(s) declare financial support was received for the research, authorship, and/or publication of this article. The research was supported by the grants from: Zhejiang Provincial Program for Medicine and Health (2022KY446, 2022KY447, 2023KY411, 2023 [2022KY446, 2022KY447, 2023KY411, 2023KY1345, 2023KY1347]; Zhejiang Provincial Program for Medicine and Health [2022E10026]; Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, China [21ywb115, 21ywb118, 20ywb143]; Social Development Science and Technology Foundation of Taizhou [2020S0180083, 2021S00156, 2021S00197, 2020S0180127]; Social Development Science and Technology Foundation of Wenling
机构署名:
本校为其他机构
院系归属:
生物科学技术学院
摘要:
Osteoporosis is a common metabolic disease in middle-aged and elderly people. It is characterized by a reduction in bone mass, compromised bone microstructure, heightened bone fragility, and an increased susceptibility to fractures. The dynamic imbalance between osteoblast and osteoclast populations is a decisive factor in the occurrence of osteoporosis. With the increase in the elderly population in society, the incidence of osteoporosis, disability, and mortality have gradually increased. Polyphenols are a fascinating class of compounds that are found in both food and medicine and exhibit a ...

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