A lysosome targetable fluorescent probe for palladium species detection base on an ESIPT phthalimide derivative

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成果类型：

期刊论文

作者：

Shen, Youming;Zhang, Xiangyang;Wu, Yanyang*;Zhang, Youyu;Liu, Xuewen;...

通讯作者：

Wu, Yanyang

作者机构：

[Shen, Youming; Zhong, Yutong; Zhang, Xiangyang; Chen, Yuandao; Liu, Xuewen] Hunan Univ Arts & Sci, Coll Chem & Mat Engn, Collaborat Innovat Ctr Efficient & Hlth Prod Fish, Hunan Prov Cooperat Innovat Ctr Construct & Dev D, Changde 415000, Peoples R China.

[Wu, Yanyang] Hunan Agr Univ, Food Sci & Technol Coll, Changsha 410000, Hunan, Peoples R China.

[Zhang, Youyu; Li, Haitao] Hunan Normal Univ, Coll Chem & Chem Engn, Minist Educ, Key Lab Chem Biol & Tradit Chinese Med Res, Changsha 410081, Hunan, Peoples R China.

通讯机构：

[Wu, Yanyang] H

Hunan Agr Univ, Food Sci & Technol Coll, Changsha 410000, Hunan, Peoples R China.

语种：

英文

关键词：

Fluorescent probe;Palladium detection;ESIPT;Phthalimide;Lysosome

期刊：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

ISSN：

1386-1425

年：

2018

卷：

205

页码：

66-71

DOI：

10.1016/j.saa.2018.06.104

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21675051]; Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [17B181]; Hunan Provincial Natural Science FoundationNatural Science Foundation of Hunan Province [2017112195]; Foundation of Hunan University of Arts and Science [17ZD03]

机构署名：

本校为通讯机构

院系归属：

食品科学技术学院

摘要：

A novel lysosome-targetable phthalimide fluorescent probe was designed for detecting palladium based on ESIPT for signal transduction. The fluorescent probe conjugating with allylcarbamate displayed weak fluorescent due to the ESIPT process hinder by allylcarbamate. But with the addition of palladium, the ESIPT emission was recovery though the palladium-catalyzed deallylation reaction and the fluorescence intensity exhibited 40-fold enhancement at 511 nm. In addition, the probe showed excellent selectivity, high sensitivity, fast responds and low limit detection for palladium with a larger Sto...

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A lysosome targetable fluorescent probe for palladium species detection base on an ESIPT phthalimide derivative

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