Network Pharmacology Suggests Mechanisms for Therapeutic Effects of Caulis Sinomenii on Avian Gout

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成果类型：

期刊论文

作者：

Li, Guanyang;Xu, Junfei;Li, Huanhuan;Yan, Wenxin;Chen, Fengting;...

通讯作者：

Yuan, Anwen;Zhang, JZ

作者机构：

[Yuan, Anwen; Zhang, Juzuo; Li, Guanyang] Hunan Agr Univ, Coll Vet Med, Dept Clin Vet Med, Changsha 410128, Peoples R China.

[Zhang, Juzuo; Xu, Junfei; Chen, Fengting; Yan, Wenxin; Li, Guanyang; Li, Huanhuan] Huaihua Univ, Coll Biol & Food Engn, Key Lab Res & Utilizat Ethnomedicinal Plant Resour, Hunan Prov Higher Educ Key Lab Intens Proc Res Mt, Huaihua 418000, Peoples R China.

[Yuan, AW; Zhang, JZ] Huaihua Univ, Coll Biol & Food Engn, 180 Huaidong Rd, Huaihua 418000, Peoples R China.

通讯机构：

[Yuan, AW; Zhang, JZ ] H

Huaihua Univ, Coll Biol & Food Engn, 180 Huaidong Rd, Huaihua 418000, Peoples R China.

语种：

英文

关键词：

Caulis sinomenii;avian gout;molecular docking;network pharmacology

期刊：

JOURNAL OF POULTRY SCIENCE

ISSN：

1346-7395

年：

2025

卷：

页码：

2025002

DOI：

10.2141/jpsa.2025002

基金类别：

Natural Science Foundation of Hunan Province [2021JJ30546, 2021JJ30547]; Fund Project of Hunan Education Depart-ment [20K099, 21A0495]; Natural Sciences Foundation of China [81830041, 81771617]

机构署名：

本校为第一机构

院系归属：

动物医学院

摘要：

Avian gout (AG) is detrimental to the survival and production performance of poultry and effective drugs are lacking. Caulis sinomenii has shown clinical efficacy against arthritis and may have potential value in AG prevention and treatment. In the present study, the components and targets of C. sinomenii and AG-related targets were identified using relevant databases. The common targets, target interactions, and signaling pathways involved in the prevention and treatment of AG by C. sinomenii were determined using software to explore the potential mechanisms of action. Sixteen components of C...

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Network Pharmacology Suggests Mechanisms for Therapeutic Effects of Caulis Sinomenii on Avian Gout

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