Epicatechin Gallate Regulation of Steroid Hormone Levels Improves Sarcopenia in C57BL/6J Mice

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成果类型：

期刊论文

作者：

Huang, Ziwei;Liu, Meifeng;Zhou, Yufei;Tang, Yiyu;Huang, Jian'an;...

通讯作者：

Liu, AL

作者机构：

[Liu, Ailing; Huang, Ziwei] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Peoples R China.

[Liu, Ailing; Liu, Zhonghua; Huang, Ziwei; Huang, Jian'an; Zhang, Sheng; Liu, Meifeng; Zhou, Yufei; Tang, Yiyu] Natl Res Ctr Engn & Technol Utilizat Bot Funct Ing, Changsha 410128, Peoples R China.

[Liu, Ailing; Liu, Zhonghua; Huang, Ziwei; Huang, Jian'an; Zhang, Sheng; Liu, Meifeng; Zhou, Yufei; Tang, Yiyu] Hunan Agr Univ, Key Lab Tea Sci, Minist Educ, Changsha 410128, Peoples R China.

[Liu, Ailing; Liu, Zhonghua; Huang, Ziwei; Huang, Jian'an; Zhang, Sheng; Liu, Meifeng; Zhou, Yufei; Tang, Yiyu] Yuelushan Lab, Changsha 410128, Peoples R China.

通讯机构：

[Liu, AL ] H

Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Peoples R China.

Natl Res Ctr Engn & Technol Utilizat Bot Funct Ing, Changsha 410128, Peoples R China.

Hunan Agr Univ, Key Lab Tea Sci, Minist Educ, Changsha 410128, Peoples R China.

Yuelushan Lab, Changsha 410128, Peoples R China.

语种：

英文

关键词：

epicatechin gallate;sarcopenia;skeletal muscle;steroid hormone

期刊：

Foods

ISSN：

2304-8158

年：

2025

卷：

期：

DOI：

10.3390/foods14142495

基金类别：

National Key RD Project; Key R&D Project of Hunan Province [2021NK1020-3]; [2022YFE0111200]

机构署名：

本校为第一且通讯机构

院系归属：

园艺园林学院

生物科学技术学院

摘要：

The decline in differentiation capacity during skeletal muscle (SkM) aging contributes to the deterioration of skeletal muscle function and impairs regenerative ability. Epicatechin gallate (ECG), a major functional component of catechins found in tea, has an unclear role in aging-related sarcopenia. In vivo experiments in 54-week-old C57BL/6J mice showed that ECG treatment improved exercise performance, muscle mass, and fiber morphology and downregulated the expression of the testosterone metabolic enzyme gene UGT2A3 in aged mice. In vitro exp...

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Epicatechin Gallate Regulation of Steroid Hormone Levels Improves Sarcopenia in C57BL/6J Mice

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