期刊论文

中文

中国兽医学报

1005-4545

2011

31

2

237-240,244

10.16303/j.cnki.1005-4545.2011.02.021

本校为其他机构

利用不同浓度的醋酸铅溶液(0,20,40,80μmol/L)作用成骨细胞24 h,研究醋酸铅对体外培养新生SD大鼠成骨细胞增殖分化和钙调蛋白(Calmodulin, CaM)的影响.结果表明,成骨细胞的增殖功能和ALP活性随着醋酸铅浓度的增加而显著降低(P

Lead acetate solutions of different concentration were used to affect osteoblasts for 24h in order to study the influnces on calmodulin（CaM） and proliferation function of osteoblasts of SD rats cultivated in vitro.The result showed that the proliferation function of osteoblasts and ALP activity were significantly reduced by the increase of lead acetate concentration（P0.05 or P0.01）,with a dose-effect relationship.Compared with control group,the ALP activity of osteoblasts affected by lead acetate was greatly decreased（P0.05）,while the mRN...