A case was reported in a Rhizomys sinensis farm in Chenzhou city Hunan province.Combined with epidemiological investigation and clinical examination,pathological anatomy and laboratory diagnosis were employed to detect the cause of disease.The results showed that the edema in Rhizomys sinensis was mainly caused by pathogenic Escherichia coli.Sensitive drugs directed to this pathogenic Escherichia coli strain were screened by antibiotic sensitive test,and h...