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Black tea increases hypertonic stress resistance in C. elegans

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成果类型:
期刊论文
作者:
Yuan, Pei;Pan, Lian-yun;Xiong, Li-gui;Tong, Jie-wen;Li, Juan;...
通讯作者:
Liu, Zhong-hua;Gong, Yu-shun
作者机构:
[Liu, Zhong-hua; Pan, Lian-yun; Yuan, Pei; Xiong, Li-gui; Li, Juan] Hunan Agr Univ, Natl Res Ctr Engn Technol Utilizat Funct Ingredie, Changsha 410128, Hunan, Peoples R China.
[Huang, Jian-an; Gong, Yu-shun; Xiong, Li-gui; Tong, Jie-wen] Hunan Agr Univ, Key Lab Tea Sci, Minist Educ, Changsha 410128, Hunan, Peoples R China.
[Huang, Jian-an; Liu, Zhong-hua; Li, Juan] Hunan Agr Univ, Collaborat Innovat Ctr Utilisat Funct Ingredients, Changsha 410128, Hunan, Peoples R China.
通讯机构:
[Liu, Zhong-hua; Gong, Yu-shun] H
Hunan Agr Univ, Natl Res Ctr Engn Technol Utilizat Funct Ingredie, Changsha 410128, Hunan, Peoples R China.
Hunan Agr Univ, Key Lab Tea Sci, Minist Educ, Changsha 410128, Hunan, Peoples R China.
Hunan Agr Univ, Collaborat Innovat Ctr Utilisat Funct Ingredients, Changsha 410128, Hunan, Peoples R China.
语种:
英文
期刊:
FOOD & FUNCTION
ISSN:
2042-6496
年:
2018
卷:
9
期:
7
页码:
3798-3806
基金类别:
This work was financially supported by the National Natural Science Foundation of China (No. 31270733), the National Key Research and Development Program of China (No. 2017YFD0400803), and the Project of the Education Department in Hunan (No. 12W005). We thank Zhang Lu from the Redox Biology Center, University of Nebraska-Lincoln, and Hu Xiaoping from the University of International Business and Economics Press for critical reading of the manuscript.
机构署名:
本校为第一且通讯机构
院系归属:
园艺园林学院
摘要:
Here we identified that BTE (black tea extract), within the studied concentration range, is more effective than GTE (green tea extract) in protecting C. elegans against hypertonic stress, by enhancing survival after exposure to various salts, and alleviating suffered motility loss and body shrinkage. The mechanism of such protection may be due to the ability of black tea to induce the conserved WNK/GCK signaling pathway and down-regulation of the expression levels of nlp-29. Intriguingly, black tea does not relieve hypertonicity-induced protein...

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