Increased prefrontal and parietal cortical thickness does not correlate with anhedonia in patients with untreated first-episode major depressive disorders

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成果类型：

期刊论文

作者：

Yang, Xin-hua;Wang, Yi;Huang, Jia;Zhu, Cui-ying;Liu, Xiao-qun;...

通讯作者：

Chan, Raymond C. K.

作者机构：

[Wang, Yi; Yang, Xin-hua; Chan, Raymond C. K.; Huang, Jia] Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Key Lab Mental Hlth, Beijing 100101, Peoples R China.

[Yang, Xin-hua; Zhu, Cui-ying] Hunan Agr Univ, Coll Business, Changsha, Hunan, Peoples R China.

[Xie, Guang-rong] Cent S Univ, Natl Technol Inst Psychiat, Key Lab Psychiat & Mental Hlth Hunan Prov, Mental Hlth Inst,Xiangya Hosp 2, Changsha, Hunan, Peoples R China.

[Cheung, Eric F. C.] Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China.

[Liu, Xiao-qun] Cent S Univ, Sch Publ Hlth, Changsha, Hunan, Peoples R China.

通讯机构：

[Chan, Raymond C. K.] C

Chinese Acad Sci, Inst Psychol, 16 Lincui Rd, Beijing 100101, Peoples R China.

语种：

英文

关键词：

Anhedonia;Caudate-cortical network;Cortical thickness;Major depressive disorder;Parietal gyrus

期刊：

PSYCHIATRY RESEARCH-NEUROIMAGING

ISSN：

0925-4927

年：

2015

卷：

234

期：

页码：

144-151

DOI：

10.1016/j.pscychresns.2015.09.014

基金类别：

Chinese Academy of SciencesChinese Academy of Sciences [XDB02030002]; National Science Fund China [81088001, 31100747, 81371492]; Beijing Training Project for the Leading Talents in ST [Z151100000315020]; Key Laboratory of Mental Health; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2015M571149]; PhD research startup foundation of Hunan Agricultural University [15RCPT04]

机构署名：

本校为其他机构

院系归属：

商学院

摘要：

Cerebral morphological abnormalities in major depressive disorder (MDD) may be modulated by antidepressant treatment and course of illness in chronic medicated patients. The present study examined cortical thickness in patients with untreated first-episode MDD to elucidate the early pathophysiology of this illness. Here, we examined cortical thickness in patients with first-episode MDD (N=27) and healthy controls (N=27) using an automated surface-based method (in FreeSurfer). By assessing the correlation between caudate volume and cortical thickness at each vertex on the cortical surface, a ca...

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Increased prefrontal and parietal cortical thickness does not correlate with anhedonia in patients with untreated first-episode major depressive disorders

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