Development and validation of an analytical method based on HPLC-ELSD for the simultaneous determination of rosmarinic acid, carnosol, carnosic acid, oleanolic acid and ursolic acid in rosemary

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成果类型：

期刊论文

作者：

Li, Penghui;Liu, Ailing;Li, Yinhua;Yuan, Bin;Xiao, Wenjun;...

通讯作者：

Zhang, Sheng;Lin, Haiyan

作者机构：

[Li, Yinhua; Liu, Zhonghua; Xiao, Wenjun; Lin, Haiyan; Zhang, Sheng; Lin, HY; Li, Penghui] Hunan Agr Univ, Natl Res Ctr Engn Technol Utilizat Funct Ingredie, Changsha 410128, Hunan, Peoples R China.

[Li, Yinhua; Liu, Zhonghua; Xiao, Wenjun; Lin, Haiyan; Zhang, Sheng; Lin, HY; Li, Penghui] Hunan Agr Univ, Collaborat Innovat Ctr Utilizat Funct Ingredients, Changsha 410128, Hunan, Peoples R China.

[Liu, Ailing; Yuan, Bin] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Hunan, Peoples R China.

通讯机构：

[Zhang, S; Lin, HY] H

Hunan Agr Univ, Natl Res Ctr Engn Technol Utilizat Funct Ingredie, Changsha 410128, Hunan, Peoples R China.

Hunan Agr Univ, Collaborat Innovat Ctr Utilizat Funct Ingredients, Changsha 410128, Hunan, Peoples R China.

语种：

英文

关键词：

abietane derivative;carnosic acid;carnosol;cinnamic acid derivative;depside;oleanolic acid;rosmarinic acid;triterpene;ursolic acid;calibration;chemistry;high performance liquid chromatography;limit of detection;procedures;radiation scattering;reproducibility;validation study;Calibration;Chromatography, High Pressure Liquid;Cinnamates;Depsides;Diterpenes, Abietane;Limit of Detection;Oleanolic Acid;Reproducibility of Results;Scattering, Radiation;Triterpenes

期刊：

Molecules

ISSN：

1420-3049

年：

2019

卷：

期：

页码：

24020323-1-24020323-8

DOI：

10.3390/molecules24020323

基金类别：

Funding: This work was funded by the Changsha Science and Technology Major Project (kq1703003).

机构署名：

本校为第一且通讯机构

院系归属：

园艺园林学院

生物科学技术学院

摘要：

The safety, efficacy and stability of natural antioxidants have been the focus of research in the food industry, with the aim of rapidly analyzing and controlling the quality of rosemary and its extracts, a novel analytical method involving high-performance liquid chromatography with evaporative light scattering detection (HPLC-ELSD) was developed for the simultaneous determination of rosmarinic acid, carnosol, carnosic acid, oleanolic acid and ursolic acid in rosemary. Chromatographic separation was conducted with gradient elution mode by usin...

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Development and validation of an analytical method based on HPLC-ELSD for the simultaneous determination of rosmarinic acid, carnosol, carnosic acid, oleanolic acid and ursolic acid in rosemary

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