An integrated strategy toward comprehensive characterization and quantification of multiple components from herbal medicine: An application study in Gelsemium elegans

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Meng-ting Zuo;Yan-chun Liu;Zhi-liang Sun;Li Lin;Qi Tang;...

通讯作者：

Zhao-ying Liu

作者机构：

[Meng-ting Zuo; Yan-chun Liu; Li Lin] College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China

Hunan Engineering Technology Research Center of Veterinary Drugs, Hunan Agricultural University, Changsha 410128, China

[Qi Tang; Pi Cheng] Hunan Key Laboratory of Traditional Chinese Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China

[Zhi-liang Sun] College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China<&wdkj&>Hunan Engineering Technology Research Center of Veterinary Drugs, Hunan Agricultural University, Changsha 410128, China

[Zhao-ying Liu] College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China<&wdkj&>Hunan Engineering Technology Research Center of Veterinary Drugs, Hunan Agricultural University, Changsha 410128, China<&wdkj&>Hunan Key Laboratory of Traditional Chinese Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China

通讯机构：

[Zhao-ying Liu] C

College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China<&wdkj&>Hunan Engineering Technology Research Center of Veterinary Drugs, Hunan Agricultural University, Changsha 410128, China<&wdkj&>Hunan Key Laboratory of Traditional Chinese Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China

语种：

英文

关键词：

Gelsemium elegans (Gardn. & Champ.) Benth;herbal medicine;LC-MS;mass spectrometry

期刊：

中草药：英文版

ISSN：

1674-6384

年：

2021

卷：

期：

页码：

17-32

DOI：

10.1016/j.chmed.2020.06.002

基金类别：

This work was supported by National Key R&D Program of Intergovernmental Key Projects (Grant No: 2018YFE0101700 ) and National Natural Science Foundation of China (Grant No. 31972737 ).

机构署名：

本校为第一且通讯机构

院系归属：

动物医学院

摘要：

Objective: To develop a powerful integrated strategy based on liquid chromatography coupled with mass spectrometry (LC-MS) systems for the comprehensive characterization and quantification of multiple components of herbal medicines. Methods: Firstly, different mobile phase additives, analysis time, and MS acquisition modes were orthogonally tested with liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (LC-QTOF/MS) in order to detect as many components of Gelsemium elegans as possible with high peak intensity. Second...

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An integrated strategy toward comprehensive characterization and quantification of multiple components from herbal medicine: An application study in Gelsemium elegans

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