Role and mechanism of catechin in skeletal muscle cell differentiation

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Li, Penghui;Liu, Ailing;Liu, Changwei;Qu, Zhihao;Xiao, Wenjun;...

通讯作者：

Zhang, Sheng

作者机构：

[Liu, Changwei; Liu, Zhonghua; Xiao, Wenjun; Zhang, Sheng; Li, Penghui; Huang, Jianan; Qu, Zhihao] Hunan Agr Univ, Minist Educ, Key Lab Tea Sci, Changsha 410128, Hunan, Peoples R China.

[Liu, Changwei; Liu, Zhonghua; Xiao, Wenjun; Zhang, Sheng; Li, Penghui; Huang, Jianan; Qu, Zhihao] Hunan Agr Univ, Natl Res Ctr Engn Technol Utilizat Funct Ingredie, Collaborat Innovat Ctr Utilizat Funct Ingredients, Changsha 410128, Hunan, Peoples R China.

[Liu, Ailing] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Hunan, Peoples R China.

通讯机构：

[Zhang, Sheng] H

Hunan Agr Univ, Minist Educ, Key Lab Tea Sci, Changsha 410128, Hunan, Peoples R China.

语种：

英文

关键词：

Atomic force microscopy;Catechins;Epicatechin gallate;Myogenic differentiation;Skeletal muscle

期刊：

JOURNAL OF NUTRITIONAL BIOCHEMISTRY

ISSN：

0955-2863

年：

2019

卷：

页码：

108225

DOI：

10.1016/j.jnutbio.2019.108225

基金类别：

National Key RD Plan [2017YFD0400803]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2019,00120]; Changsha Science and Technology Major Project [kq1804003]; Hunan Provincial Innovation Foundation for Postgraduate [CX2018B421]

机构署名：

本校为第一且通讯机构

院系归属：

园艺园林学院

生物科学技术学院

摘要：

Muscle degeneration and cachexia caused by aging and chronic diseases seriously reduce the quality of life of patients. Catechins in tea enhance skeletal muscle performance, but the specific function and mechanism require further exploration. Myogenic differentiation is accompanied by extensive changes in cell morphology and gene expression patterns. In this study, we measured the number, length, diameter, and transcriptional levels of MyoD, MyoG, and MyHC of myotubes after C2C12 cell differentiation to assess changes in response to four different catechin monomers: epicatechin, epigallocatech...

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Role and mechanism of catechin in skeletal muscle cell differentiation

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