期刊论文

Liu, Zhao-Ying

英文

Journal of Analytical Toxicology

0146-4760

2020

44

4

378-390

10.1093/jat/bkz100

National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31972737]; Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [18A088]

本校为第一且通讯机构

Gelsemium elegans (G. elegans) has been used in traditional Chinese medicine. This plant is highly toxic to humans, but can promote the growth of pigs and goats in the veterinary clinic. It is a very complex mixture containing tens or hundreds of different components. Therefore, multiple-component pharmacokinetic studies of G. elegans are a major challenge due to the lack of authentic standards of the components. The purpose of this study was to investigate the plasma pharmacokinetics of multiple components after a single oral dose of G. elegans in goat using a sensitive ultra-performance liqu...