To investigate effects of different concentrations of earthworm fibrinolytic enzyme(EFE) on proliferation of normal human liver cells LO2 cells in vitro and palmitic acid(PA) induced LO2 cells, and find out the optimal concentration of EFE, LO2 cells were treated with different concentration of EFE(100, 200, 400, 600, 800 and 1 000 u/m L), then MTT method was used to to determine the OD value after 6 h, 12 h and 24 h in different groups. Meanwhile LO2 cells induced by 20 μg/m L PA for 24 h were also treated with different concentration o...