期刊论文

中文

中兽医医药杂志

1000-6354

2018

37

3

60-63

10.13823/j.cnki.jtcvm.2018.03.020

国家重点研发计划子课题（2016YFD0501000） 河南省基础与前沿技术研究（152300410199） 河南省科技攻关项目（132102110036）

本校为其他机构

研究板蓝根多糖(Radix Isatidis polysaccharide,RIPS)对醋酸铅诱导雄性小鼠生长发育的影响.将3周龄60只健康雄性昆明系小鼠随机分为6个组:即对照组,RIPS 100 mg/kg组,铅模型组,RIPS低、中、高剂量(50 mg/kg、100 mg/kg、 200 mg/kg)治疗组,连续7 d腹腔注射醋酸铅20 mg/kg制备小鼠铅中毒模型,造模后对板蓝根多糖治疗组分别饮水给予不同浓度的RIPS,1次/d,连续给药28 d.观测每组小鼠日均采食量、体质量增长、脏器系数.结果显示,模型组日均采食量少于对照组和RIPS组,RIPS治疗组日均采食量随RIPS剂量的增加而明显增加;染毒各组小鼠体质量均显著降低(P

To study the effects of Radix Isatidis polysaccharide on growth performance of male mice challenged by lead acetate, 60 male Kunming mice at the age of 3 weeks were randomly divided into 5 treatment groups and 1 control group, each treatment with 10 mice. Four treatment groups mice were intraperitonealy injected with lead acetate solution at concentrations of 20 mg/kg for 7 days to produce the lead-poisoning model, respectively, and the control group mice was injected with the same volume of double sterile water. After the model was established, various doses of RIPS were administered via drin...