期刊论文

Relaxant effects of polyphenols from Phyllanthus urinaria on contraction of intestinal smooth muscle of rabbit in vitro

中文

中兽医医药杂志

1000-6354

2019

38

4

64-67

10.13823/j.cnki.jtcvm.2019.04.019

(G(S)CX1703):国家级大学生创新创业训练计划项目 (SCX1703):湖南省大学生创新项目 (XCX17004):湖南农业大学大学生创新项目 (2017YFD0501403):国家重点研发计划专项:畜禽用新剂型研制开发

本校为第一机构

目的:本试验以兔离体肠平滑肌为研究对象,考察叶下珠多酚对离体肠肌收缩的影响,并探讨其作用机制。方法:利用BL-420E生物机能系统,观察叶下珠多酚对离体肠肌自发性收缩的影响;观察叶下珠多酚对工具药氯化钡、酚妥拉明及组胺作用下离体肠肌活动的影响,并记录收缩频率和振幅。结果:叶下珠多酚可抑制兔离体肠肌自发性收缩的振幅,且呈剂量依赖性;叶下珠多酚可显著或极显著抑制由氯化钡、酚妥拉明及组胺引起的离体肠肌的挛缩（P

Objective:To clear the effects of polyphenols from Phyllanthus urinaria on contraction of intestinal smooth muscle of rabbit in vitro. Method:The experiments were performed in isolated intestinal smooth muscle of rabbits. By analyzing the frequency and amplitude of contraction,the inhibition of polyphenols from Phyllanthus urinaria on normal intestinal smooth muscle contraction and histamine,phentolamine and barium chloride(BaCl2)-treated intestinal muscle contraction were compared. Result:The results showed that polyphenols from Phyllanthus ur...