期刊论文

Relaxant effect of alkaloids from Phyllanthus urinaria on contraction of intestinal smooth muscle of rabbit mechanism in vitro

中文

中兽医医药杂志

1000-6354

2019

38

5

40-43

10.13823/j.cnki.jtcvm.2019.05.010

(G(S)CX1703):国家级大学生创新创业训练计划项目 (SCX1703):湖南省大学生创新项目 (XCX17004):湖南农业大学大学生创新项目 (2017YFD0501403):国家重点研发计划专项:畜禽用新剂型研制开发

本校为第一机构

目的:以兔离体小肠平滑肌为研究对象,研究叶下珠生物碱对兔离体肠肌收缩的影响,并探讨其作用机制。方法:利用BL-420E生物机能系统,观察叶下珠生物碱对兔离体肠肌自发性收缩和工具药乙酰胆碱、阿托品、新斯的明、组胺作用下离体肠肌活动的影响,观察并记录收缩频率和振幅。结果:叶下珠生物生物碱可显著抑制兔离体肠肌自发性收缩的频率和振幅（P

Objective:To research the relaxant effect of alkaloids from Phyllanthus urinaria on contraction of intestinal smooth muscle of rabbit mechanism in vitro,and to explore the mechanism of the action of rabbit isolated small intestine smooth muscle.Methods:The effects of alkaloids on the spontaneous contraction of intestinal muscle in rabbits and the activity of BL-420 E in vitro under the action of acetylcholine,atropine,neostimine and histamine were observed and the shrinkage frequency and amplitude were observed and recorded by using the biological function system of the leaves.Results:The alka...