期刊论文

Effects of polyphenols from Phyllanthus urinaria on gastrointestinal motility in mice

中文

中兽医医药杂志

1000-6354

2019

38

3

59-61

10.13823/j.cnki.jtcvm.2019.03.017

(G(S)CX1703):国家级大学生创新创业训练计划项目 (SCX1703):湖南省大学生创新项目 (XCX17004):湖南农业大学大学生创新项目 (2017YFD0501403):国家重点研发计划专项:畜禽用新剂型研制开发

本校为第一机构

目的:探究叶下珠多酚对小鼠肠蠕动的影响.方法:采用回流法提取叶下珠多酚.将50只健康小白鼠随机分为生理盐水对照组、叶下珠多酚试验组(13.40 mg/mL、6.70 mg/mL、3.35 mg/mL)、阿托品组(5.00 mg/kg),灌胃给药.灌药后30 min(阿托品组15 min)灌服蓝色墨水,20 min处死小鼠,打开腹腔,分离肠道并测量其长度.结果:与生理盐水对照组相比,叶下珠多酚可抑制胃肠运动,且具有浓度依赖性.

Objective:To investigate the effects of polyphenols from Phyllanthus urinaria on gastrointestinal motility in mice.Methods:The polyphenols was extracted by reflux method. Fifty healthy mice were randomly divided into 5 groups(n=10),normal saline control group,treatment groups(13.40mg/mL,6.70mg/mL,3.35mg/mL),atropine group(5.00mg/kg),and medicine were given by gavage.30 minutes after treatment(15 minutes in atropine group),blue ink was fed. 20 minutes after administration,mice were killed by euthanasia and intestine was separated. Results:The results showed that comparison with the control grou...