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Sensitive label-free electrochemical immunoassay by electrocatalytic amplification

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成果类型:
期刊论文
作者:
Chen, Chenrui;Liu, Dengyou;Wu, Zaisheng*;Luo, Qimei;Shen, Guo-Li;...
通讯作者:
Wu, Zaisheng
作者机构:
[Chen, Chenrui; Shen, Guo-Li; Yu, Ru-Qin; Wu, Zaisheng] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.
[Luo, Qimei; Liu, Dengyou] Hunan Agr Univ, Coll Sci, Changsha 410128, Hunan, Peoples R China.
通讯机构:
[Wu, Zaisheng] H
Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.
语种:
英文
关键词:
Human immunoglobulin E (IgE);Methylene blue (MB);Gold nanoparticles (GNPs)
期刊:
Electrochemistry Communications
ISSN:
1388-2481
年:
2009
卷:
11
期:
10
页码:
1869-1872
基金类别:
National Basic Research Program [2007CB310500]; National Natural Science Foundation of China [90817101, 20675028, 20775023, 20865006]; Hunan Provincial Natural Science Foundation [07JJ6101, 07IJ3017]; Hunan Provincial Education Department [08A065]
机构署名:
本校为其他机构
院系归属:
理学院
摘要:
A label-free electrochemical immunosensor for the detection of protein analytes without redox-active centers is for the first time developed based on the combination of gold nanoparticles and the mediated charge transport through the multilayer films that is related to an electrocatalytic process. Given the low detection limit, high sensitivity and selectivity, the success achieved here seems plausibly to serve as a significant step toward th...

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