期刊论文

Tian, Y

英文

Bioresource Technology

0960-8524

2023

377

128964

10.1016/j.biortech.2023.128964

CRediT authorship contribution statement Xi-Yu Duan: Conceptualization, Methodology, Data curation, Writing – original draft. Hu-Hu Liu: acquisition, Resources, Writing – review & editing. Li-Ping Song: Methodology, Data curation. Chong Wang: Formal analysis. Hui Yang: Validation, Formal analysis. Xiang-Yang Lu: Formal analysis, acquisition. Xiao-Jun Ji: Resources, Validation. Yun Tian: acquisition, Supervision, Writing – review & editing.

本校为第一且通讯机构

Cordycepin, a nucleoside compound with a variety of biological activities, has been extensively applied in the nutraceutical and pharmaceutical industries. The advancement of microbial cell factories using agro-industrial residues provides a sustainable pathway for cordycepin biosynthesis. Herein, the cordycepin production was enhanced by the modification of glycolysis and pentose phosphate pathway in engineered Yarrowia lipolytica. Then, cordycepin production based on economical and renewable substrates (sugarcane molasses, waste spent yeast, and diammonium hydrogen phosphate) was analyzed. F...