Characterizing core microbiota and regulatory functions of the pig gut microbiome

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成果类型：

期刊论文

作者：

Hu, Jun;Chen, Jianwei;Ma, Libao;Hou, Qiliang;Zhang, Yong;...

通讯作者：

Wang, Xiangru;Yan, XH

作者机构：

[Hu, Jun; Hou, Qiliang; Yan, Xianghua; Wei, Hong; Wang, Xiangru; Ma, Libao] Huazhong Agr Univ, Coll Anim Sci & Technol, Frontiers Sci Ctr Anim Breeding & Sustainable Prod, Natl Key Lab Agr Microbiol,Hubei Hongshan Lab,Coll, Wuhan 430070, Hubei, Peoples R China.

[Hu, Jun; Hou, Qiliang; Yan, Xianghua; Wang, Xiangru; Ma, Libao] Cooperat Innovat Ctr Sustainable Pig Prod, Wuhan 430070, Hubei, Peoples R China.

[Hu, Jun; Hou, Qiliang; Yan, Xianghua; Ma, Libao] Hubei Prov Engn Lab Pig Precis Feeding & Feed Safe, Wuhan 430070, Hubei, Peoples R China.

[Chen, Jianwei] BGI Res, Qingdao 266555, Shandong, Peoples R China.

[Chen, Jianwei] Univ Copenhagen, Dept Biol, Lab Genom & Mol Biomed, DK-2100 Copenhagen, Denmark.

通讯机构：

[Yan, XH ; Wang, XR] 1

1 Shizishan St, Wuhan 430070, Hubei, Peoples R China.

语种：

英文

关键词：

gut microbiome;pig;core gut microbes;gene catalog;germ-free mice

期刊：

ISME Journal

ISSN：

1751-7362

年：

2024

卷：

期：

DOI：

10.1093/ismejo/wrad037

基金类别：

National Natural Science Foundation of Chin [31925037, 32230099]; Hubei Hongshan Laboratory [2021hszd018]; Fundamental Research Funds for the Central Universities [2662023DKPY002]; National Natural Science Foundation of China [32102499]; National Postdoctoral Program for Innovative Talents of China [BX20190133]; Postdoctoral Science Foundation of China [2019M662671]; Natural Science Foundation of Hubei Province [2022CFB358, 2021CFA018]; Hubei Provincial Postdoctoral Innovative Post Project of China

机构署名：

本校为其他机构

院系归属：

动物科学技术学院

摘要：

Domestic pigs (Sus scrofa) are the leading terrestrial animals used for meat production. The gut microbiota significantly affect host nutrition, metabolism, and immunity. Hence, characterization of the gut microbial structure and function will improve our understanding of gut microbial resources and the mechanisms underlying host-microbe interactions. Here, we investigated the gut microbiomes of seven pig breeds using metagenomics and 16S rRNA gene amplicon sequencing. We established an expanded gut microbial reference catalog comprising 17 020 160 genes and identified 4910 metagenome-assemble...

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Characterizing core microbiota and regulatory functions of the pig gut microbiome

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