A chromosome-level genome assembly for the rabbit tapeworm Taenia pisiformis

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成果类型：

期刊论文

作者：

Pu, Lixia;Liu, Zhongli;Guo, Aijiang;Wu, Bin;Liu, Guo-hua;...

通讯作者：

Xuepeng Cai<&wdkj&>Shuai Wang

作者机构：

[Pu, Lixia; Li, Xiaolu; Zhang, Shaohua; Liu, Zhongli; Guo, Aijiang; Cai, Xuepeng; Guo, Xiaola; Wang, Shuai] Chinese Acad Agr Sci, Lanzhou Vet Res Inst, State Key Lab Vet Etiol Biol, Key Lab Vet Parasitol Gansu Prov, Lanzhou 730046, Gansu, Peoples R China.

[Jian, Jianbo; Wu, Bin] BGI Shenzhen, BGI Genom, Shenzhen 518083, Peoples R China.

[Liu, Guo-hua] Hunan Agr Univ, Coll Vet Med, Res Ctr Parasites & Vectors, Changsha 410128, Hunan, Peoples R China.

[Wang, Shuai] Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou 225009, Jiangsu, Peoples R China.

通讯机构：

[Xuepeng Cai; Shuai Wang] S

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, Gansu Province, China<&wdkj&>Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, Jiangsu, China<&wdkj&>State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, Gansu Province, China

语种：

英文

关键词：

Tapeworm;Taenia pisiformis;Genome;Evolution

期刊：

Gene

ISSN：

0378-1119

年：

2022

卷：

834

页码：

146650

DOI：

10.1016/j.gene.2022.146650

基金类别：

This work was supported by grants from the Natural Science Foundation of Gansu Province, China (Grant No. 21JR7RA027), and State Key Laboratory of Veterinary Etiological Biology (SKLVEB2021YQRC01). Authors’ contribution S.W. and X.C. conceived the project and acquired funding. A.G., S.Z., X.G., J.J. and X.L. collected samples and performed Hi-C experiments, and Illumina library preparation. L.P., Z.L., B.W. and G.L. performed genome size estimates, genome assembly, genome annotation, and evolution analysis. L.P. and Z.L. wrote the manuscript, S.W. and X.C. revised the manuscript.

机构署名：

本校为其他机构

院系归属：

动物医学院

摘要：

Taenia pisiformis is one of the most widespread gastrointestinal parasites and its larvae (cysticercosis) causes significant economic loss to rabbit industry. No efficient drug is available for this disease to date. To better understand its genomics, we assembled a 211-Mb high quality genome of T. pisiformis at chromosome level with a scaffold N50 size of 20 Mbp. Totally, 12,097 protein-coding genes was predicted from the genome. Genome-level phylogenetic analysis confirmed the taxonomic affiliations with other tapeworms and revealed that T. pi...

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A chromosome-level genome assembly for the rabbit tapeworm Taenia pisiformis

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