Ningxiang pig-derived lactobacillus reuteri modulates host intramuscular fat deposition via branched-chain amino acid metabolism

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成果类型：

期刊论文

作者：

Yang, Mei;Xie, Qian;Wang, Jing;Zha, Andong;Chen, Jiashun;...

通讯作者：

Tan, B;Yin, Yulong;Yin, YL

作者机构：

[Chen, Jiashun; Kang, Meng; Tan, Bie; Tan, B; Wang, Jing; Deng, Qiuchun; Yang, Mei; Xie, Qian; Jiang, Qian] Hunan Agr Univ, Coll Anim Sci & Technol, Hunan Prov Key Lab Prod Qual Regulat Livestock & P, Changsha 410128, Hunan, Peoples R China.

[Chen, Jiashun; Kang, Meng; Tan, Bie; Tan, B; Wang, Jing; Yin, Yulong; Deng, Qiuchun; Yang, Mei; Zha, Andong; Xie, Qian; Jiang, Qian; Yin, YL] Yuelushan Lab, Changsha 410128, Hunan, Peoples R China.

[Yin, Yulong; Zha, Andong; Yin, YL] Chinese Acad Sci, Inst Subtrop Agr, Key Lab Agroecol Proc Subtrop Reg, Natl Engn Lab Pollut Control & Waste Utilizat Live, Changsha 410125, Hunan, Peoples R China.

通讯机构：

[Tan, B ] H

[Yin, YL ] C

[Yin, YL] Y

Hunan Agr Univ, Coll Anim Sci & Technol, Hunan Prov Key Lab Prod Qual Regulat Livestock & P, Changsha 410128, Hunan, Peoples R China.

Yuelushan Lab, Changsha 410128, Hunan, Peoples R China.

语种：

英文

期刊：

Microbiome

ISSN：

2049-2618

年：

2025

卷：

期：

页码：

1-12

DOI：

10.1186/s40168-024-02013-6

基金类别：

This work was supported by the National Natural Science Foundation of China (No. U20A2054, 32302761), Biological Breeding-National Science and Technology Major Project (No.2023ZD04046)，and the Natural Science Foundation of Hunan Province (No. 2024JJ1004).

机构署名：

本校为第一且通讯机构

院系归属：

动物科学技术学院

摘要：

BackgroundGut microbiota has been extensively demonstrated to modulate host lipid metabolism. Higher intramuscular fat (IMF) accumulation in Chinese indigenous breed pigs is associated with their special gut microbiota structure. However, the specific microbes and metabolic pathways responsible for lipid deposition are still poorly understood.ResultsIn the present study, a comparative analysis of the gut microbiota and metabolome in obese Ningxiang (NX) pigs and lean Duroc x Landrace x Yorkshire (DLY) pigs was conducted. The results revealed a higher abundance of gut lactobacilli and a correla...

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Ningxiang pig-derived lactobacillus reuteri modulates host intramuscular fat deposition via branched-chain amino acid metabolism

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