Heat shock protein 71 restricts mutation of porcine reproductive and respiratory syndrome virus nsp2 in vitro

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xie, Fengyu;Kang, Lei;Chen, Mengli;Zhang, Tong;Li, Zongjie;...

通讯作者：

Li, MX;Ma, Zhiyong;Liu, K

作者机构：

[Li, MX; Li, Manxiang; Xie, Fengyu] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan Province, Peoples R China.

[Li, Zongjie; Kang, Lei; Shao, Donghua; Liu, K; Li, Beibei; Ma, Zhiyong; Liu, Ke; Wei, Jianchao; Xie, Fengyu; Qiu, Yafeng; Ma, ZY; Zhang, Tong; Chen, Mengli] Chinese Acad Agr Sci, Shanghai Vet Res Inst, 518 Ziyue Rd, Shanghai 200241, Peoples R China.

[Kang, Lei; Chen, Mengli] Nanjing Agr Univ, Coll Vet Med, Nanjing, Peoples R China.

通讯机构：

[Li, MX ] H

[Ma, ZY; Liu, K ] C

Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan Province, Peoples R China.

Chinese Acad Agr Sci, Shanghai Vet Res Inst, 518 Ziyue Rd, Shanghai 200241, Peoples R China.

语种：

英文

关键词：

Heat shock protein 71;Mutation;Porcine reproductive and respiratory syndrome virus nsp2

期刊：

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

ISSN：

0147-9571

年：

2024

卷：

109

页码：

102179

DOI：

10.1016/j.cimid.2024.102179

基金类别：

National Basic Research Program (973 Plan) [2014CB542702]; Shanghai Natural Science Fund [21ZR1477100]; National Key Research and Development Program [2022YFD1800502]

机构署名：

本校为第一且通讯机构

院系归属：

动物医学院

摘要：

porcine reproductive and respiratory syndrome (PRRS), caused by porcine reproductive and respiratory syndrome virus (PRRSV) infection, is an important swine infectious disease that causes substantial losses worldwide each year. PRRSV is a positive-sense single-stranded RNA virus that is highly susceptible to mutation and recombination, making vaccine and drug research for the disease extremely difficult. In this study, the binding of PRRSV nsp2 to HSP71 protein was detected by using the IP/MS technique. And the inhibitory effect of HSP71 on nsp2 antagonistic activity was validated by measuring...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Heat shock protein 71 restricts mutation of porcine reproductive and respiratory syndrome virus nsp2 in vitro

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问