L-Theanine alleviates heat stress through modulation of gut microbiota and immunity

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成果类型：

期刊论文

作者：

Liu, Sha;Wang, Bin;Lin, Ling;Xu, Wei;Gong, Zhi-Hua*;...

通讯作者：

Gong, Zhi-Hua;Xiao, WJ

作者机构：

[Gong, Zhi-Hua; Xiao, Wen-Jun; Xiao, WJ; Liu, Sha; Lin, Ling; Xu, Wei; Wang, Bin; Gong, ZH] Hunan Agr Univ, Key Lab Tea Sci, Minist Educ, Changsha 410128, Hunan, Peoples R China.

[Gong, Zhi-Hua; Xiao, Wen-Jun; Liu, Sha; Lin, Ling; Xu, Wei; Wang, Bin] Hunan Agr Univ, Natl Res Ctr Engn Technol Utilizat Bot Funct Ingre, Changsha, Peoples R China.

[Gong, Zhi-Hua; Xiao, Wen-Jun; Liu, Sha; Lin, Ling; Xu, Wei; Wang, Bin] Hunan Agr Univ, Sino Kenya Joint Lab Tea Sci, Changsha, Peoples R China.

通讯机构：

[Xiao, WJ ; Gong, ZH] H

Hunan Agr Univ, Key Lab Tea Sci, Minist Educ, Changsha 410128, Hunan, Peoples R China.

语种：

英文

关键词：

l-theanine;anti-heat stress;gut microbiota;immunity

期刊：

Journal of the Science of Food and Agriculture

ISSN：

0022-5142

年：

2024

卷：

104

期：

页码：

2059-2072

DOI：

10.1002/jsfa.13095

基金类别：

This work was supported by the National Natural Science Foundation of China (grant number 32372329), the National Key Research and Development Program of China (No. 2022YFD1600805), and the Major Science and Technology Project of Hunan Province (No. 2021NK1020).

机构署名：

本校为第一且通讯机构

院系归属：

园艺园林学院

摘要：

BACKGROUND: Heat stress (HS) damages the intestines, disrupting gut microbiota and immune balance. l-Theanine (LTA), found in tea, alleviates oxidative stress and cell apoptosis under HS; however, its effects on gut microbiota and immunity under HS remain unclear. To investigate this, we administered LTA doses of 100, 200, and 400 mg·kg−1·d−1 to C57BL/6J mice. On day 44, the model group and LTA intervention group were subjected to continuous 7-day HS treatment for 2 h per day. RESULTS: The results demonstrated that LTA intervention improved...

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L-Theanine alleviates heat stress through modulation of gut microbiota and immunity

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