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Long-term Effects of Lysine Restriction on Liver Global Proteins, Meat Quality, and Blood Biochemical Parameters in Pigs

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成果类型:
期刊论文
作者:
Liu, Zhaojin;Yuan, Yong;Yin, Jie;Li, Tiejun*;Zhang, Hongfu;...
通讯作者:
Li, Tiejun;He, Jianhua
作者机构:
[Liu, Zhaojin; Li, Tiejun; He, Jianhua; Yuan, Yong; Zhang, Hongfu] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Hunan, Peoples R China.
[Yin, Jie; Li, Tiejun] Chinese Acad Sci, Inst Subtrop Agr, Key Lab Agroecol Proc Subtrop Reg, Changsha, Hunan, Peoples R China.
[Zhang, Hongfu] Chinese Acad Agr Sci, Inst Anim Sci, State Key Lab Anim Nutr, Beijing, Peoples R China.
[Liu, Zhaojin] Guangdong Haid Grp Co LTD, Guangzhou, Guangdong, Peoples R China.
[Liu, Zhaojin] Haid Cent Res Inst, Guangzhou, Guangdong, Peoples R China.
通讯机构:
[Li, TJ; He, JH] H
Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Hunan, Peoples R China.
语种:
英文
关键词:
Lysine;proteomics;biochemical parameters;meat quality;transporter;pig.
期刊:
PROTEIN AND PEPTIDE LETTERS
ISSN:
0929-8665
年:
2018
卷:
25
期:
4
页码:
405-416
基金类别:
National Basic Research Program of China (973)National Basic Research Program of China [2013CB127301]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31272463, 31472106]; Key Projects in the National Science & Technology Pillar Program [2013BAD21B04]
机构署名:
本校为第一且通讯机构
院系归属:
动物科学技术学院
摘要:
Background: Our previous study suggested that short-term lysine restriction improved feed intake and gut microbiota in piglets. Thus, in this study, we further used proteomics technology to investigate the potential mechanism associated with long-term lysine restriction in pigs. In addition, blood biochemical parameters, meat quality, and muscle nutrient transporters were also evaluated in lysine restricted pigs. Results: The results showed that 131 proteins in the liver were markedly altered in response to dietary lysine restriction, with 54 being downregulated and 77 being upregulated, which...

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