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EasyMetagenome: A user-friendly and flexible pipeline for shotgun metagenomic analysis in microbiome research

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成果类型:
期刊论文
作者:
Bai, Defeng;Chen, Tong;Xun, Jiani;Ma, Chuang;Luo, Hao;...
通讯作者:
Chen, T;Wen, T;Chen, SF;Li, GL;Gao, Yunyun;Liu, YX
作者机构:
[Li, Xin; Yang, Haifei; Liu, Yong-Xin; Bai, Defeng; Gao, Yunyun; Wan, Xiulin; Yousuf, Salsabeel; Zhang, Tianyuan; Hou, Huiyu; Xun, Jiani; Zeng, Meiyin; Luo, Hao; Lv, Hujie; Ma, Chuang; Wang, Yao] Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Genome Anal Lab, Minist Agr & Rural Affairs, Shenzhen, Guangdong, Peoples R China.
[Chen, T; Chen, Tong] China Acad Chinese Med Sci, Natl Resource Ctr Chinese Mat Med, State Key Lab Qual Ensurance & Sustainable Use Da, Beijing, Peoples R China.
[Wen, Tao] Nanjing Agr Univ, Coll Resource & Environm Sci, Nanjing, Jiangsu, Peoples R China.
[Chen, Shifu] Gannan Med Univ, LifeX Inst, Sch Med Technol, Ganzhou, Peoples R China.
[Li, GL; Li, Guoliang] Jiangxi Agr Univ, Coll Forestry, Jiangxi Prov Key Lab Conservat Biol, Nanchang, Jiangxi, Peoples R China.
通讯机构:
[Chen, SF ] G
[Li, GL ] J
[Gao, YY; Chen, T ; Liu, YX ] C
[Wen, T ] N
China Acad Chinese Med Sci, Natl Resource Ctr Chinese Mat Med, State Key Lab Qual Ensurance & Sustainable Use Da, Beijing, Peoples R China.
语种:
英文
关键词:
metagenome;microbiome;microbiota;pipeline;visualization
期刊:
iMeta
ISSN:
2770-5986
年:
2025
卷:
4
期:
1
页码:
e70001
基金类别:
National Natural Science Foundation of China [32470055, U23A20148]; Agricultural Science and Technology Innovation Program [CAAS-ZDRW202308]; China Postdoctoral Science Foundation [2024M753580]; Fundamental Research Funds for the Central Public Welfare Research Institutes [ZZ13-YQ-095]; Scientific and Technology Innovation Project of China Academy of Chinese Medical Sciences [CI2021A04115]; Scientific and technological innovation project of China Academy of Chinese Medical Sciences [CI2023E002, 2060302]
机构署名:
本校为其他机构
院系归属:
动物医学院
摘要:
Shotgun metagenomics has become a pivotal technology in microbiome research, enabling in-depth analysis of microbial communities at both the high-resolution taxonomic and functional levels. This approach provides valuable insights of microbial diversity, interactions, and their roles in health and disease. However, the complexity of data processing and the need for reproducibility pose significant challenges to researchers. To address these challenges, we developed EasyMetagenome, a user-friendly pipeline that supports multiple analysis methods, including quality control and host removal, read...

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