Upregulation of microRNA-32 is associated with tumorigenesis and poor prognosis in patients with hepatocellular carcinoma

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Yang, Huiqiong;Li, Yusheng;Zhong, Xiaoming;Luo, Pei;Luo, Ping;...

通讯作者：

Ma, Yushui;Cong, Xianling

作者机构：

[Yang, Huiqiong; Xie, Ruting; Fu, Da; Ma, Yushui] Tongji Univ, Sch Med, Shanghai Peoples Hosp 10, Dept Nucl Med & Pathol, 301 Middle Yanchang Rd, Shanghai 200072, Peoples R China.

[Yang, Huiqiong; Luo, Pei; Li, Wenping] Hunan Agr Univ, Coll Vet Med, Fac Vet, Changsha 410128, Hunan, Peoples R China.

[Li, Yusheng] Cent South Univ, Xiangya Hosp, Dept Orthoped, Changsha 410008, Hunan, Peoples R China.

[Zhong, Xiaoming] Jiangxi Prov Tumor Hosp, Dept Radiol, Nanchang 330029, Jiangxi, Peoples R China.

[Luo, Ping] Nanchang Third Hosp, Dept Breast Canc, Nanchang 330002, Jiangxi, Peoples R China.

通讯机构：

[Ma, Yushui] T

[Cong, Xianling] J

Tongji Univ, Sch Med, Shanghai Peoples Hosp 10, Dept Nucl Med & Pathol, 301 Middle Yanchang Rd, Shanghai 200072, Peoples R China.

Jilin Univ, China Japan Union Hosp, Tissue Bank, 126 Xiantai Blvd, Changchun 130033, Jilin, Peoples R China.

语种：

英文

关键词：

Gene Expression Omnibus;hepatocellular carcinoma;microRNA-32 expression;overall survival;prognosis

期刊：

ONCOLOGY LETTERS

ISSN：

1792-1074

年：

2018

卷：

期：

页码：

4097-4104

DOI：

10.3892/ol.2018.7879

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81201535, 81302065, 81472202, 81772932, 81472209, 81702243]; Jilin Provincial Science and Technology Department [20140414061GH]; Shanghai Natural Science FoundationNatural Science Foundation of Shanghai [12ZR1436000, 16ZR1428900]; Shanghai Municipal Commission of Health and Family Planning [201440398, 201540228]

机构署名：

本校为其他机构

院系归属：

动物医学院

摘要：

MicroRNA-32 (miR-32) is associated with tumor progression and poor prognosis in certain malignant tumors. However, the function and clinical relevance of miR-32 in human hepatocellular carcinoma (HCC) has not yet been elucidated. The present study aimed to investigate the expression and prognostic value of miR-32 from liver samples in patients with HCC. The expression of miR-32 was analyzed in HCC and healthy tissues using Gene Expression Omnibus datasets. Reverse transcription-quantitative polymerase chain reaction was used to analyze the leve...

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Upregulation of microRNA-32 is associated with tumorigenesis and poor prognosis in patients with hepatocellular carcinoma

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