A high-performance approach for predicting donor splice sites based on short window size and imbalanced large samples

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成果类型：

期刊论文

作者：

Zeng, Ying;Yuan, Hongjie;Yuan, Zheming*;Chen, Yuan*

通讯作者：

Yuan, Zheming;Chen, Yuan

作者机构：

[Zeng, Ying; Yuan, Hongjie; Yuan, Zheming] Hunan Agr Univ, Hunan Engn & Technol Res Ctr Agr Big Data Anal &, Changsha 410128, Hunan, Peoples R China.

[Zeng, Ying] Hunan Agr Univ, Orient Sci & Technol Coll, Changsha 410128, Hunan, Peoples R China.

[Yuan, Zheming] Hunan Agr Univ, Hunan Prov Key Lab Biol & Control Plant Dis & Ins, Changsha 410128, Hunan, Peoples R China.

[Chen, Yuan] Hunan Agr Univ, Hunan Prov Key Lab Crop Germplasm Innovat & Utili, Changsha 410128, Hunan, Peoples R China.

通讯机构：

[Chen, Yuan; Yuan, Zheming] H

Hunan Engineering & Technology Research Center for Agricultural Big Data Analysis & Decision-making, Hunan Agricultural University, Changsha, 410128, Hunan, China.

Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha, 410128, Hunan, China.

Hunan Provincial Key Laboratory of Crop Germplasm Innovation and Utilization, Hunan Agricultural University, Changsha, 410128, Hunan, China.

语种：

英文

关键词：

Donor splice site;Short window size;χ2-DT;Chi-square test;Balanced decision table

期刊：

Biology Direct

ISSN：

1745-6150

年：

2019

卷：

期：

页码：

1-15

DOI：

10.1186/s13062-019-0236-y

基金类别：

Scientific Research Foundation of Education Office of Hunan Province,China [17A096]; National Natural Science Foundation of ChinaNationalNatural Science Foundation of China [61701177]; Hunan Provincial NaturalScience Foundation of ChinaNatural Science Foundation of Hunan Province[2018JJ3225]; Science foundation open project of Hunan Provincial KeyLaboratory of Crop Germplasm Innovation and Utilization [18KFXM08]

机构署名：

本校为第一机构

院系归属：

植物保护学院

东方科技学院

摘要：

Background: Splice sites prediction has been a long-standing problem in bioinformatics. Although many computational approaches developed for splice site prediction have achieved satisfactory accuracy, further improvement in predictive accuracy is significant, for it is contributing to predict gene structure more accurately. Determining a proper window size before prediction is necessary. Overly long window size may introduce some irrelevant features, which would reduce predictive accuracy, while the use of short window size with maximum informa...

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A high-performance approach for predicting donor splice sites based on short window size and imbalanced large samples

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