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Effects of ethanol intake on anti-oxidant responses and the lifespan of Caenorhabditis elegans

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成果类型:
期刊论文
作者:
Wu, Zhong-Qin;Li, Ke;Ma, Jin-Kui;Li, Zong-Jun*
通讯作者:
Li, Zong-Jun
作者机构:
[Wu, Zhong-Qin; Li, Ke; Li, Zong-Jun] Hunan Agr Univ, Coll Food Sci & Technol, Hunan Prov Key Lab Food Sci & Biotechnol, Changsha 410128, Hunan, Peoples R China
[Ma, Jin-Kui] Zhaoqing Univ, Sch Food & Pharmaceut Engn, Zhaoqing, Peoples R China
通讯机构:
[Li, Zong-Jun] H
Hunan Agr Univ, Coll Food Sci & Technol, Hunan Prov Key Lab Food Sci & Biotechnol, Changsha 410128, Hunan, Peoples R China.
语种:
英文
关键词:
Alcohol;alcohol;apoptosis celular;Caenorhabditis elegans;Caenorhabditis elegans;cell apoptosis;duración de vida;estrés oxidativo;lifespan;oxidative stress
期刊:
CyTA - Journal of Food
ISSN:
1947-6337
年:
2019
卷:
17
期:
1
页码:
288-296
基金类别:
This work was supported by the Major Science and Technology Program in Hainan province under grant [ZDKJ2016003]. We thank the Caenorhabditis Genetics Center for providing C. elegans.
机构署名:
本校为第一且通讯机构
院系归属:
食品科学技术学院
摘要:
The effects of alcohol stress on Caenorhabditis elegans were investigated. Nematodes were exposed to 1–5% alcohol, after which lifespan, movement, reactive oxygen species, antioxidant enzymes, cell apoptosis, and expression of apoptosis-related proteins were evaluated. Low concentrations of alcohol (1–2%) significantly enhanced total antioxidant capacity, along with an observable increase in normal locomotion. Total antioxidant activity was significantly lower at high (4–5%) than at low (1–2%) concentrations of alcohol. These results sugges...

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