Real-time monitoring of contractile properties of H9C2 cardiomyoblasts by using a quartz crystal microbalance

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成果类型：

期刊论文

作者：

Zhou, Tiean*;Zhou, Zhen;Zhou, Shuyue;Huang, Fushen

通讯作者：

Zhou, Tiean

作者机构：

[Huang, Fushen; Zhou, Zhen; Zhou, Tiean; Zhou, Shuyue] Hunan Agr Univ, Cell Mech & Biosensing Inst, Changsha 410128, Hunan, Peoples R China.

[Zhou, Zhen; Zhou, Tiean] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Hunan, Peoples R China.

[Huang, Fushen] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan, Peoples R China.

[Zhou, Tiean] Hunan Agr Univ, Cell Mech & Biosensing Inst, 405 Life Sci Bldg, Changsha 410128, Hunan, Peoples R China.

通讯机构：

[Zhou, Tiean] H

Hunan Agr Univ, Cell Mech & Biosensing Inst, 405 Life Sci Bldg, Changsha 410128, Hunan, Peoples R China.

语种：

英文

期刊：

ANALYTICAL METHODS

ISSN：

1759-9660

年：

2016

卷：

期：

页码：

488-495

DOI：

10.1039/c5ay02835c

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21275048]; Key Project of Hunan Provincial Science & Technology Department [2013TT1009]

机构署名：

本校为第一且通讯机构

院系归属：

动物医学院

生物科学技术学院

摘要：

Conventional cardiac physiology experiments investigate in vitro beat frequency using cells isolated from adult or neonatal rat hearts. Recently, there is an increased interest in measuring the mechanical properties of cardiomyocytes including their contraction force and viscoelasticity. In this study, we used a quartz crystal microbalance (QCM) to study the viscoelasticity of populations of H9C2 cardiomyoblasts under different stimuli. First, we observed the effects of osmotic pressure and found that H9C2 cardiomyoblasts became stiffer under h...

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Real-time monitoring of contractile properties of H9C2 cardiomyoblasts by using a quartz crystal microbalance

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