期刊论文

Zeng, JG;Yang, Zihui

英文

Journal of Pharmaceutical and Biomedical Analysis

0731-7085

2025

255

116667

10.1016/j.jpba.2025.116667

This work was supported by supported by Shanxi key lab. for modernization of TCVM (Grant No. SXKL2022001 ), National Key Research and Development Program (Grant No. 2022YFD1801105 ). CRediT authorship contribution statement Jianguo Zeng: Writing – review & editing, Conceptualization, Project administration, Resources. Zihui Yang: Writing – review & editing, Supervision, Conceptualization, acquisition. Lin Wang: Formal analysis, Investigation. Xinhao Wang: Formal analysis, Investigation. Na Sun: Writing – review & editing. Zhiyong Wu: Writing – original draft, Methodology, Investigation.

本校为通讯机构

Allocryptopine (ALL), a principal active component of the novel veterinary medicine Bopu Powder®, has gained widespread application in the poultry farming sector for the effective management of Escherichia coli ( E. coli ) diarrhea. In order to explore the metabolites and the pivotal enzymes associated with ALL, this study was conducted employing an in vitro chicken liver microsomal incubation. The metabolites of ALL were analyzed and identified by combining isotope tracing technology with the application of mass spectrometry fragmentation pat...