Meta-analysis and machine learning reveal the antiobesity effects of melatonin on obese rodents

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成果类型：

期刊论文

作者：

Li, Yuying;Sun, Xihang;Wang, Mansheng;Jiang, Yayun;Ge, Qian Qian;...

通讯作者：

Shi, PJ;Yao, K;Yin, J

作者机构：

[Jiang, Yayun; Ge, Qian Qian; Hou, Zhenping; Li, Yuying; Wang, Mansheng; Shi, Pengjun; Sun, Xihang] Chinese Acad Agr Sci, Inst Bast Fiber Crops, Changsha, Peoples R China.

[Jiang, Yayun; Ge, Qian Qian; Yin, Jie] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Peoples R China.

[Yao, Kang; Li, Tiejun] Chinese Acad Sci, Inst Subtrop Agr, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, Changsha, Peoples R China.

[Shi, Pengjun] Chinese Acad Agr Sci, Inst Bast Fiber Crops, Changsha 410205, Hunan, Peoples R China.

[Yao, Kang; Yao, K] Chinese Acad Sci, Inst Subtrop Agr, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, Changsha 410125, Hunan, Peoples R China.

通讯机构：

[Yao, K ; Shi, PJ ] C

[Yin, J ] H

Chinese Acad Agr Sci, Inst Bast Fiber Crops, Changsha 410205, Hunan, Peoples R China.

Chinese Acad Sci, Inst Subtrop Agr, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, Changsha 410125, Hunan, Peoples R China.

Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410000, Hunan, Peoples R China.

语种：

英文

关键词：

lipid metabolism;machine learning;melatonin;meta-analysis;obesity mice;obesity rat

期刊：

Obesity Reviews

ISSN：

1467-7881

年：

2024

卷：

期：

页码：

e13701

DOI：

10.1111/obr.13701

基金类别：

Central Public-interest Scientific Institution Basal Research Fund; Natural Science Foundation of Changsha Municipal [kq2208249]; Agricultural Science and Technology Innovation Project Special Fund of Chinese Academy of Agricultural Sciences; National Key R&D Program of China [2021YFD1300402]; TaiShan Industrial Experts Program [tscy20190121]; [1610242022001-02]; [1610242023002]

机构署名：

本校为通讯机构

院系归属：

动物科学技术学院

摘要：

Melatonin appears to be a promising supplement for obesity treatment. The antiobesity effects of melatonin on obese rodents are influenced by various factors, including the species, sex, the dosage of melatonin, treatment duration, administration via, daily treatment time, and initial body weight (IBW). Therefore, we conducted a meta-analysis and machine learning study to evaluate the antiobesity effect of melatonin on obese mice or rats from 31 publications. The results showed that melatonin significantly reduced body weight, serum glucose (GL...

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Meta-analysis and machine learning reveal the antiobesity effects of melatonin on obese rodents

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