Comparison of collagen extracted from channel catfish skin with acid and enzymatic. The orthogonal test results show that the optimal processing conditions in enzymatic method are: distilled water as extraction agent, amount of enzyme is 4 000 U/g, temperature is 55℃, time is 6 h, solid-liquid ratio is 1∶5, and the extraction rate is 49.32%; the optimal processing conditions in acid method are: the concentration of acetic acid is 0.5 mol/L, temperature is 30℃, time is 96 h, solid-liquid ratio is 1∶60, and the extraction rate is 55.18%. The ...