Baicalin-copper complex modulates gut microbiota, inflammatory responses, and hormone secretion in don-challenged piglets

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成果类型：

期刊论文

作者：

Zha, Andong;Cui, Zhijuan;Qi, Ming;Liao, Simeng;Yin, Jia;...

通讯作者：

Liao, Peng

作者机构：

[Liao, Simeng; Zha, Andong; Cui, Zhijuan; Tan, Bie; Qi, Ming; Liao, Peng] Chinese Acad Sci, Inst Subtrop Agr, Lab Anim Nutr Physiol & Metab Proc, Key Lab Agroecol Proc Subtrop Reg,Natl Engn Lab P, Changsha 410125, Peoples R China.

[Liao, Simeng; Zha, Andong; Qi, Ming] Univ Chinese Acad Sci, Beijing 100008, Peoples R China.

[Cui, Zhijuan; Tan, Bie] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Hunan, Peoples R China.

[Yin, Jia] Hunan Normal Univ, Coll Life Sci, Hunan Prov Key Lab Anim Funct & Regulat, Changsha 410081, Hunan, Peoples R China.

通讯机构：

[Liao, Peng] C

Chinese Acad Sci, Inst Subtrop Agr, Lab Anim Nutr Physiol & Metab Proc, Key Lab Agroecol Proc Subtrop Reg,Natl Engn Lab P, Changsha 410125, Peoples R China.

语种：

英文

关键词：

baicalin-copper complex;deoxynivalenol;hormone;inflammatory cytokines;intestinal microbiota;piglets

期刊：

ANIMALS

ISSN：

2076-2615

年：

2020

卷：

期：

页码：

1-15

DOI：

10.3390/ani10091535

基金类别：

Funding: This research was supported by the National Key R&D Program of China (2018YFD0500205, 2018YFD0800103), Technical Innovation Guidance Project of Guangxi Zhuang Autonomous Region Science and Technology Department (2018AC01007), Fujian Provincial Science and Technology Department and Chinese Academy of Sciences Supporting Project of STS Program (2019T3033), and the Innovative practice training program for college students of Chinese Academy of Sciences (KCJH801622015016).

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院系归属：

动物科学技术学院

摘要：

The present experiment assessed the inflammatory responses, hormone secretion, and gut microbiota of weanling piglets administered baicalin-copper complex (BCU) or deoxynivalenol (DON) supplementation diets. Twenty-eight piglets were randomly assigned to four groups: control diet (Con group), a 4 mg DON/kg diet (DON group), a 5 g BCU/kg diet (BCU group), a 5 g BCU + 4 mg DON/kg diet (DBCU group). After 14 days, the results showed that dietary BCU supplementation remarkably increased the relative abundance of Clostrium bornimense and decreased t...

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Baicalin-copper complex modulates gut microbiota, inflammatory responses, and hormone secretion in don-challenged piglets

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