Developments in near-infrared fluorescent probes for G-quadruplexes structures

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成果类型：

期刊论文

作者：

Han, Jiaona;Li, Jun;Luo, Xingyu;Feng, Guangfu;Zhang, Jiaheng

通讯作者：

Han, JN;Zhang, JH;Feng, GF;Luo, XY;Li, J

作者机构：

[Zhang, Jiaheng; Han, Jiaona] Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Peoples R China.

[Zhang, Jiaheng; Zhang, JH] Zhengzhou Univ, Coll Chem, Zhengzhou 450001, Peoples R China.

[Feng, Guangfu; Feng, GF] Hunan Agr Univ, Sch Biosci & Biotechnol, Changsha 410128, Peoples R China.

[Luo, Xingyu; Luo, XY] Guangxi Univ, Sch Chem & Chem Engn, Guangxi Key Lab Electrochem Energy Mat, Nanning 530004, Peoples R China.

[Li, Jun; Li, J] Zhengzhou Univ, Sch Agr Sci, Zhengzhou 450001, Peoples R China.

通讯机构：

[Han, JN ; Feng, GF ] H

[Li, J ; Zhang, JH ] Z

[Luo, XY ] G

Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Peoples R China.

Zhengzhou Univ, Coll Chem, Zhengzhou 450001, Peoples R China.

语种：

英文

关键词：

G-quadruplexes;Nucleic acids;Near-infrared fluorescent probes;Bioimaging

期刊：

Coordination Chemistry Reviews

ISSN：

0010-8545

年：

2024

卷：

520

页码：

216157

DOI：

10.1016/j.ccr.2024.216157

基金类别：

CRediT authorship contribution statement Jiaona Han: Conceptualization, Writing – original draft, Resources. Jun Li: Investigation, Validation. Xingyu Luo: acquisition, Investigation, Writing – review & editing. Guangfu Feng: Validation, Writing – review & editing. Jiaheng Zhang: acquisition, Supervision, Writing – review & editing.

机构署名：

本校为通讯机构

院系归属：

生物科学技术学院

摘要：

The G-quadruplex (G4) represents a noncanonical guanine-rich nucleic acid secondary structure characterized by the presence of two or more G-quartets stabilized through Hoogsteen hydrogen bonding. These structures play essential roles in various biological processes including DNA replication, gene expression regulation, telomere maintenance, and genomic stability. Effectively visualizing and precisely detecting G4 structures and their dynamic changes in cells and in vivo are crucial for elucidating the relationship between different G4 structures and functions within complex biological systems...

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Developments in near-infrared fluorescent probes for G-quadruplexes structures

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