Whole-genome sequencing and analysis of the Chinese herbal plant Gelsemium elegans

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Liu, Yisong;Tang, Qi;Cheng, Pi;Zhu, Mingfei;Zhang, Hui;...

通讯作者：

Sun, Zhiliang;Liu, Zhaoying

作者机构：

[Liu, Yisong; Liu, Zhaoying; Sun, Zhiliang] Hunan Agr Univ, Hunan Engn Technol Res Ctr Vet Drugs, Changsha 410128, Peoples R China.

[Wu, Changqiao; Liu, Yisong; Liu, Zhaoying; Tang, Qi; Cheng, Pi; Sun, Zhiliang] Hunan Agr Univ, Hunan Key Lab Tradit Chinese Vet Med, Changsha 410128, Peoples R China.

[Liu, Yisong; Huang, Chongyin; Liu, Zhaoying; Zuo, Mengting; Sun, Zhiliang] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Peoples R China.

[Zhang, Hui; Liu, Jiazhe; Zhu, Mingfei] Next Biosci Inst, Wuhan 430000, Peoples R China.

通讯机构：

[Sun, ZL; Liu, ZY] H

Hunan Agr Univ, Hunan Engn Technol Res Ctr Vet Drugs, Changsha 410128, Peoples R China.

Hunan Agr Univ, Hunan Key Lab Tradit Chinese Vet Med, Changsha 410128, Peoples R China.

Hunan Agr Univ, Coll Vet Med, Changsha 410128, Peoples R China.

语种：

英文

关键词：

Gelsemium elegans;Nanopore sequencing;Genome assembly;Hi-C;Genome annotation;Monoterpene indole alkaloid

期刊：

药学学报(英文)

ISSN：

2211-3835

年：

2020

卷：

期：

页码：

374-382

DOI：

10.1016/j.apsb.2019.08.004

基金类别：

This study was financially supported by Hunan Provincial Natural Science Foundation of China (grant 2017JJ1017), National Key R&D Program of China (grant 2017YFD0501403), National Natural Science Foundation of China (grant 31400275), and Hunan Provincial Natural Science Foundation of China (2018JJ2172).

机构署名：

本校为第一且通讯机构

院系归属：

动物医学院

摘要：

Background: Gelsemium elegans (G. elegans) (2n = 2x = 16) is genus of flowering plants belonging to the Gelsemicaeae family. Method: Here, a high-quality genome assembly using the Oxford Nanopore Technologies (ONT) platform and high-throughput chromosome conformation capture techniques (Hi-C) were used. Results: A total of 56.11 Gb of raw GridION X5 platform ONT reads (6.23 Gb per cell) were generated. After filtering, 53.45 Gb of clean reads were obtained, giving 160 × coverage depth. The de novo genome assemblies 335.13 Mb, close to the 338 ...

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Whole-genome sequencing and analysis of the Chinese herbal plant Gelsemium elegans

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