Grass carp (Ctenopharyngodon idellus) which has importantly economic value is the most cultured freshwater fish in China, even in the world. The hemorrhagic disease caused by grass carp reovirus (GCRV) has greatly affected the sustainable development of grass carp aquaculture. GCRV vaccine is an important method to prevent and control hemorrhagic disease, but the multi-subtype and variation characteristics of GCRV limit the preventive effect of GCRV vaccine. Organismal immune ability is closely related to genetic factors, so many progresses hav...
