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Epidermal growth factor containing culture supernatant enhances intestine development of early-weaned pigs in vivo: Potential mechanisms involved

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成果类型:
期刊论文
作者:
Bedford, Andrea;Chen, Tao;Huynh, Evanna;Zhu, Cuilan;Medeiros, Samantha;...
通讯作者:
Li, Julang
作者机构:
[Medeiros, Samantha; Bedford, Andrea; de Lange, Cornelis; Zhu, Cuilan; Chen, Tao; Li, Julang; Huynh, Evanna; Wey, Doug] Univ Guelph, Dept Anim & Poultry Sci, Guelph, ON N1G 2W1, Canada.
[Chen, Tao] Hunan Agr Univ, Coll Vet Med, Changsha, Hunan, Peoples R China.
通讯机构:
[Li, Julang] U
Univ Guelph, Dept Anim & Poultry Sci, Guelph, ON N1G 2W1, Canada.
语种:
英文
关键词:
Epidermal growth factor;Intestine development;Lactococcus lactis;Weaned pig
期刊:
Journal of Biotechnology
ISSN:
0168-1656
年:
2015
卷:
196-197
页码:
9-19
基金类别:
Ontario Pork; Natural Sciences and Engineering Research Council of CanadaNatural Sciences and Engineering Research Council of Canada (NSERC)CGIAR [CRDPJ387415-09]; Ontario Ministry of Agriculture, Food Rural Affairs; ABVista; Grand Valley Fortifiers
机构署名:
本校为其他机构
院系归属:
动物医学院
摘要:
We have previously generated epidermal factor expressing Lactococcus lactis (EGF-LL) using a bioengineering approach, and shown that EGF-LL fermentation supernatant enhanced newly weaned pigs growth. The objective of the current study was to further understand the mechanisms behind this improved performance. Sixty-four piglets were weaned at 3 weeks of age and then fed ad libitum according to a 2-phase feeding program. Four pens with 8 pigs per pen were assigned to each of two treatments for 3 weeks: (1) EGF containing supernatant from EGF-LL culture (SuperEGF) or (2) blank M17GE media (Contro...

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