Aberrant default mode network homogeneity in patients with first-episode treatment-naive melancholic depression

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成果类型：

期刊论文

作者：

Cui, Xilong;Guo, Wenbin;Wang, Yi;Yang, Tian-xiao;Yang, Xin-hua;...

通讯作者：

Xie, Guangrong

作者机构：

[Guo, Wenbin; Cui, Xilong; Tan, Changlian; Xie, Guangrong] Cent S Univ, Mental Hlth Inst, Xiangya Hosp 2, Key Lab Psychiat & Mental Hlth Hunan Prov, Changsha 410011, Hunan, Peoples R China.

[Wang, Yi; Yang, Tian-xiao] Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Key Lab Mental Hlth, Beijing, Peoples R China.

[Yang, Xin-hua] Hunan Agr Univ, Inst Educ, Changsha, Hunan, Peoples R China.

[Wang, Yefei; Gong, Jingbo] Hunan Univ Chinese Med, Dept Appl Psychol, Changsha, Hunan, Peoples R China.

[Xie, Guangrong] Bldg 139,Renmin Middle Rd, Changsha 410011, Hunan, Peoples R China.

通讯机构：

[Xie, Guangrong] B

Bldg 139,Renmin Middle Rd, Changsha 410011, Hunan, Peoples R China.

语种：

英文

关键词：

*Default mode network;*Melancholic major depressive disorder;*Network homogeneity;*Resting-state imaging

期刊：

International Journal of Psychophysiology

ISSN：

0167-8760

年：

2017

卷：

112

页码：

46-51

DOI：

10.1016/j.ijpsycho.2016.12.005

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81371492, 81260210, 81571310, 81630033, 81361120396]; National Key Basic Research ProgramNational Basic Research Program of China [2016YFC1307104]; Natural Science Foundation of Guangxi Province for Distinguished Young Scientists [2014GXNSFGA118010]

机构署名：

本校为其他机构

院系归属：

教育学院

摘要：

Background: Melancholic depression is a relatively homogenous subtype of major depressive disorders (MDD). The condition has several endogenous symptoms and represents strong biological components. However, its specific neurobiological mechanisms remain unknown. Previous neuroimaging findings indicated that default mode network (DMN) is closely related to MDD. The present study examined the network homogeneity (NH) of the DMN in patients with melancholic MDD. Methods: A total of 33 first-episode, treatment-naive melancholic MDD patients and 32 healthy controls underwent a resting-state functio...

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Aberrant default mode network homogeneity in patients with first-episode treatment-naive melancholic depression

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