Microarray Based Functional Analysis of Myricetin and Proteomic Study on Its Anti-Inflammatory Property.

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成果类型：

期刊论文

作者：

Li, Tao;Zhu, Jihe;Deng, Fangming;Wu, Weiguo;Zheng, Zhibing;...

通讯作者：

Lu, Xiangyang;Qin, Si

作者机构：

[Lu, XY; Qin, S; Li, Tao; Deng, Fangming; Wu, Weiguo; Zheng, Zhibing; Lu, Xiangyang; Lv, Chenghao; Qin, Si; Li, Yong; Zhu, Jihe] Hunan Agr Univ, Coll Food Sci & Technol, Key Lab Food Sci & Biotechnol Hunan Prov, Core Res Program 1515, Changsha 410128, Hunan, Peoples R China.

[Xiang, Wei; Lu, XY; Qin, S; Lu, Xiangyang; Qin, Si] Hunan Agr Univ, Coll Biosci & Biotechnol, Hunan Coinnovat Ctr Utilizat Bot Funct Ingredient, Changsha 410128, Hunan, Peoples R China.

[Qin, Si] Kagoshima Univ, Fac Agr, United Grad Sch Agr Sci, Korimoto 1-21-24, Kagoshima 8900065, Japan.

通讯机构：

[Lu, XY; Qin, S] H

[Qin, Si] K

Hunan Agr Univ, Coll Food Sci & Technol, Key Lab Food Sci & Biotechnol Hunan Prov, Core Res Program 1515, Changsha 410128, Hunan, Peoples R China.

Hunan Agr Univ, Coll Biosci & Biotechnol, Hunan Coinnovat Ctr Utilizat Bot Funct Ingredient, Changsha 410128, Hunan, Peoples R China.

Kagoshima Univ, Fac Agr, United Grad Sch Agr Sci, Korimoto 1-21-24, Kagoshima 8900065, Japan.

语种：

英文

期刊：

BioMed Research International

ISSN：

2314-6133

年：

2019

卷：

2019

页码：

3746326

DOI：

10.1155/2019/3746326

基金类别：

This work was partially supported by Natural Science Foundation of China and Hunan Province, Key Scientific Research Fund of Hunan Provincial Science and Technology Department (2017NK2093), Core Research Program 1515 and double first-class construction project of Hunan Agricultural University (No. SYL201802025) to Si Qin. The authors would like to thank Key Laboratory for Food Science and Biotechnology of HunanProvince, CollegeofFoodScience and Technology, Hunan Agricultural University for providing the facilities to carry out this study.

机构署名：

本校为第一且通讯机构

院系归属：

食品科学技术学院

生物科学技术学院

摘要：

Myricetin has been reported as a promising chemopreventive compound with multiple biofunctions. To evaluate its influence on gene expressions in genome-wide set and further investigate its anti-inflammatory property, the present study performed Gene Ontology and Ingenuity Pathway Analysis (IPA) to describe the basic gene expression characteristics by myricetin treatment in HepG2 cells, confirmed its multi-biofunction by real-time fluorescent quantitative PCR (RT-qPCR), and further verified its anti-inflammatory property by Western blotting and bio-plex-based cytokines assay. The IPA data showe...

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Microarray Based Functional Analysis of Myricetin and Proteomic Study on Its Anti-Inflammatory Property.

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